Methods for behavioral testing of spinal cord injured rats

J Šedý, L Urdzíková, P Jendelová, E Syková - … & Biobehavioral Reviews, 2008 - Elsevier
Behavioral outcome in rats with spinal cord injury (SCI) is the most important factor for
evaluating the extent of injury and treatment efficacy. For this purpose, a number of …

[PDF][PDF] Mechanisms of neurogenic pulmonary edema development

J Šedý, J Zicha, J Kuneš, P Jendelová, E Syková - Physiol Res, 2008 - biomed.cas.cz
Neurogenic pulmonary edema is a life-threatening complication, known for almost 100
years, but its etiopathogenesis is still not completely understood. This review summarizes …

HPMA-RGD hydrogels seeded with mesenchymal stem cells improve functional outcome in chronic spinal cord injury

A Hejčl, J Šedý, M Kapcalová, DA Toro… - Stem cells and …, 2010 - liebertpub.com
Chronic spinal cord injury (SCI) is characterized by tissue loss and a stable functional deficit.
While several experimental therapies have proven to be partly successful for the treatment of …

Blood–spinal cord barrier permeability in experimental spinal cord injury: dynamic contrast‐enhanced MRI

DM Cohen, CB Patel, P Ahobila‐Vajjula… - NMR in Biomedicine …, 2009 - Wiley Online Library
After a primary traumatic injury, spinal cord tissue undergoes a series of pathobiological
changes, including compromised blood–spinal cord barrier (BSCB) integrity. These vascular …

Pathogenetic mechanisms of neurogenic pulmonary edema

J Šedý, J Kuneš, J Zicha - Journal of neurotrauma, 2015 - liebertpub.com
Neurogenic pulmonary edema (NPE) is a life-threatening complication of central nervous
system (CNS) injuries. This review summarizes current knowledge about NPE etiology and …

tPA promotes ADAMTS-4-induced CSPG degradation, thereby enhancing neuroplasticity following spinal cord injury

S Lemarchant, M Pruvost, M Hébert, M Gauberti… - Neurobiology of …, 2014 - Elsevier
Although tissue plasminogen activator (tPA) is known to promote neuronal remodeling in the
CNS, no mechanism of how this plastic function takes place has been reported so far. We …

Contribution of α‐ and β‐Adrenergic Mechanisms to the Development of Pulmonary Edema

B Rassler - Scientifica, 2012 - Wiley Online Library
Endogenous or exogenous catecholamines can induce pulmonary edema (PE). This may
occur in human pathologic conditions such as in pheochromocytoma or in neurogenic …

Grafted human embryonic progenitors expressing neurogenin-2 stimulate axonal sprouting and improve motor recovery after severe spinal cord injury

FE Perrin, G Boniface, C Serguera, N Lonjon, A Serre… - PLoS …, 2010 - journals.plos.org
Background Spinal cord injury (SCI) is a widely spread pathology with currently no effective
treatment for any symptom. Regenerative medicine through cell transplantation is a very …

Early functional outcomes and histological analysis after spinal cord compression injury in rats

N Lonjon, P Kouyoumdjian, M Prieto, L Bauchet… - … of Neurosurgery: Spine, 2010 - thejns.org
Object Neuroprotective and repair strategies in spinal cord injuries (SCIs) have been so far
largely unsuccessful. One of the prerequisites is the use of appropriate preclinical models to …

Effects of propofol on excitatory and inhibitory amino acid neurotransmitter balance in rats with neurogenic pulmonary edema induced by subarachnoid hemorrhage

L Zhang, J Jin, J Yao, Z Yue, Y Wei, W Yang, S Fu… - Neurocritical care, 2016 - Springer
Introduction Propofol exhibits neuroprotective effects mediated by the inhibition of excitatory
amino acid (EAA) neurotransmitter release and potentiation of inhibitory amino acid (IAA) …