Pathogenicity and Virulence of Legionella: Intracellular replication and host response

D Chauhan, SR Shames - Virulence, 2021 - Taylor & Francis
Bacteria of the genus Legionella are natural pathogens of amoebae that can cause a severe
pneumonia in humans called Legionnaires' Disease. Human disease results from inhalation …

The relationship between mucins and ulcerative colitis: a systematic review

E Bankole, E Read, MA Curtis, JF Neves… - Journal of Clinical …, 2021 - mdpi.com
Mucins are a family of glycosylated proteins which are the primary constituents of mucus and
play a dynamic role in the regulation of the protective mucosal barriers throughout the …

Salmonella-liberated dietary L-arabinose promotes expansion in superspreaders

SJ Ruddle, LM Massis, AC Cutter, DM Monack - Cell Host & Microbe, 2023 - cell.com
The molecular understanding of host-pathogen interactions in the gastrointestinal (GI) tract
of superspreader hosts is incomplete. In a mouse model of chronic, asymptomatic …

Chitinases as key virulence factors in microbial pathogens: understanding their role and potential as therapeutic targets

GJ Jeong, F Khan, N Tabassum, YM Kim - International Journal of …, 2023 - Elsevier
Chitinases are crucial for the survival of bacterial and fungal pathogens both during host
infection and outside the host in the environment. Chitinases facilitate adhesion onto host …

Protein sociology of ProA, Mip and other secreted virulence factors at the Legionella pneumophila surface

L Scheithauer, MS Karagöz, BE Mayer… - Frontiers in Cellular and …, 2023 - frontiersin.org
The pathogenicity of L. pneumophila, the causative agent of Legionnaires' disease, depends
on an arsenal of interacting proteins. Here we describe how surface-associated and …

Bacterial chitinases and their role in human infection

JR Devlin, J Behnsen - Infection and Immunity, 2023 - Am Soc Microbiol
It has been widely appreciated that numerous bacterial species express chitinases for the
purpose of degrading environmental chitin. However, chitinases and chitin-binding proteins …

Chitinolytic enzymes contribute to the pathogenicity of Aliivibrio salmonicida LFI1238 in the invasive phase of cold-water vibriosis

A Skåne, PK Edvardsen, G Cordara, JSM Loose… - BMC microbiology, 2022 - Springer
Background Aliivibrio salmonicida is the causative agent of cold-water vibriosis in salmonids
(Oncorhynchus mykiss and Salmo salar L.) and gadidae (Gadus morhua L.). Virulence …

Salmonella enterica serovar Typhimurium chitinases modulate the intestinal glycome and promote small intestinal invasion

JR Devlin, W Santus, J Mendez, W Peng, A Yu… - PLoS …, 2022 - journals.plos.org
Salmonella enterica serovar Typhimurium (S. Typhimurium) is one of the leading causes of
food-borne illnesses worldwide. To colonize the gastrointestinal tract, S. Typhimurium …

The Legionella collagen-like protein employs a distinct binding mechanism for the recognition of host glycosaminoglycans

S Rehman, AK Antonovic, IE McIntire, H Zheng… - Nature …, 2024 - nature.com
Bacterial adhesion is a fundamental process which enables colonisation of niche
environments and is key for infection. However, in Legionella pneumophila, the causative …

Legionella pneumophila—Virulence Factors and the Possibility of Infection in Dental Practice

J Talapko, E Frauenheim, M Juzbašić, M Tomas… - Microorganisms, 2022 - mdpi.com
Legionella pneumophila is defined as a bacterium that can cause severe pneumonia. It is
found in the natural environment and in water, and is often found in water tanks. It can be an …