The lymphatic system plays critical roles in tissue fluid homeostasis and immunity and has
been implicated in the development of many different pathologies, ranging from …

Near-infrared fluorescence (NIRF) imaging is an attractive modality for early cancer
detection with high sensitivity and multi-detection capability. Due to convenient modification …

It is well documented that cells secrete exosomes, which can transfer biomolecules that
impact recipient cells' functionality in a variety of physiologic and disease processes. The …

This review examines the current understanding of how the lymphatic vessel network can
optimize lymph flow in response to various mechanical forces. Lymphatics are organized as …

Bioimaging enables the visualisation of biological processes at the microscopic and
macroscopic levels, finding applications from cellular tracking to whole body scanning for …

Visualization of the lymphatic system is clinically necessary during diagnosis or treatment of
many conditions and diseases; it is used for identifying and monitoring lymphedema, for …

Key points Obesity induces lymphatic leakiness, decreases initial lymphatic vessel density,
impairs collecting vessel pumping and decreases transport of macromolecules. Obesity …

Direct in vivo imaging of lymph flow is key to understanding lymphatic system function in
normal and disease states. Optical microscopy techniques provide the resolution required …

Obesity is a major risk factor for inflammatory dermatologic diseases, including atopic
dermatitis and psoriasis. In addition, recent studies have shown that obesity impairs …

Given the known mechanosensitivity of the lymphatic vasculature, we sought to investigate
the effects of dynamic wall shear stress (WSS) on collecting lymphatic vessels while …