Recent advances in the pharmacological diversification of quinazoline/quinazolinone hybrids
Due to the pharmacological activities of quinazoline and quinazolinone scaffolds, it has
aroused great interest in medicinal chemists for the development of new drugs or drug …
aroused great interest in medicinal chemists for the development of new drugs or drug …
Synthesis and pharmacological activities of pyrazole derivatives: A review
Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …
that possesses almost all types of pharmacological activities. The presence of this nucleus in …
Biologically active pyrazole derivatives
Nitrogen-containing heterocyclic compounds and their derivatives have historically been
invaluable as a source of therapeutic agents. Pyrazole, which has two nitrogen atoms and …
invaluable as a source of therapeutic agents. Pyrazole, which has two nitrogen atoms and …
Overview of recent developments of pyrazole derivatives as an anticancer agent in different cell line
FE Bennani, L Doudach, Y Cherrah, Y Ramli… - Bioorganic …, 2020 - Elsevier
Pyrazole is a five-membered aromatic heterocyclic ring with two adjacent nitrogen atoms C 3
H 3 N 2 H. The presence of this nucleus in pharmacological agents of various therapeutic …
H 3 N 2 H. The presence of this nucleus in pharmacological agents of various therapeutic …
[HTML][HTML] Pyrazole and pyrazoline derivatives as antimalarial agents: A key review
Malaria poses a severe public health risk and a significant economic burden in disease-
endemic countries. One of the most severe issues in malaria control is the development of …
endemic countries. One of the most severe issues in malaria control is the development of …
Synthesis, characterization, catalytic, DNA binding and antibacterial activities of Co (II), Ni (II) and Cu (II) complexes with new Schiff base ligand
OA El-Gammal, FS Mohamed, GN Rezk… - Journal of Molecular …, 2021 - Elsevier
Abstract New Schiff base (E)-4-(3-cyano-4, 6-dimethylpyridin-2-ylamino)-N′-(1-(2-
hydroxyphenyl) ethylidene) benzohydrazide (HL) was synthesized by condensation of 2 …
hydroxyphenyl) ethylidene) benzohydrazide (HL) was synthesized by condensation of 2 …
The therapeutic voyage of pyrazole and its analogs: a review
Pyrazole, a five membered heteroaromatic ring with two nitrogen atoms is of immense
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …
Recent advances in bioactive pyrazoles
ŞG Küçükgüzel, S Şenkardeş - European Journal of Medicinal Chemistry, 2015 - Elsevier
Pyrazole is a five membered and two-nitrogen containing heterocyclic ring. These structures
have been investigated in the development of novel compounds with hypoglycemic …
have been investigated in the development of novel compounds with hypoglycemic …
Pyrazole containing natural products: Synthetic preview and biological significance
A large number of structurally diverse natural compounds containing azole nucleus
constitute an important class of biologically active heterocycles that are gaining more …
constitute an important class of biologically active heterocycles that are gaining more …
Development of novel pyrazole, imidazo [1, 2-b] pyrazole, and pyrazolo [1, 5-a] pyrimidine derivatives as a new class of COX-2 inhibitors with immunomodulatory …
Searching for new compounds with anti-inflammatory properties is a significant target since
inflammation is a major cause of pain. A series of pyrazole, imidazopyrazolone, and …
inflammation is a major cause of pain. A series of pyrazole, imidazopyrazolone, and …