Medium chain carboxylic acids production from waste biomass: Current advances and perspectives

Q Wu, X Bao, W Guo, B Wang, Y Li, H Luo… - Biotechnology …, 2019 - Elsevier
Alternative chemicals to diverse fossil-fuel-based products is urgently needed to mitigate the
adverse impacts of fossil fuel depletion on human development. To this end, researchers …

Advances in systems metabolic engineering of autotrophic carbon oxide-fixing biocatalysts towards a circular economy

M Pavan, K Reinmets, S Garg, AP Mueller… - Metabolic …, 2022 - Elsevier
High levels of anthropogenic CO 2 emissions are driving the warming of global climate. If
this pattern of increasing emissions does not change, it will cause further climate change …

Acetogenic bacteria utilize light-driven electrons as an energy source for autotrophic growth

S Jin, Y Jeon, MS Jeon, J Shin… - Proceedings of the …, 2021 - National Acad Sciences
Acetogenic bacteria use cellular redox energy to convert CO2 to acetate using the Wood–
Ljungdahl (WL) pathway. Such redox energy can be derived from electrons generated from …

Valorization of C1 gases to value-added chemicals using acetogenic biocatalysts

J Bae, Y Song, H Lee, J Shin, S Jin, S Kang… - Chemical Engineering …, 2022 - Elsevier
In times of global warming and upcoming fossil fuel shortages, the demand for the
replacement of current fossil fuel-based chemical production via the development of …

Genome-wide CRISPRi screen identifies enhanced autolithotrophic phenotypes in acetogenic bacterium Eubacterium limosum

J Shin, J Bae, H Lee, S Kang, S Jin… - Proceedings of the …, 2023 - National Acad Sciences
Acetogenic bacteria are a unique biocatalyst that highly promises to develop the sustainable
bioconversion of carbon oxides (eg, CO and CO2) into multicarbon biochemicals. Genotype …

Functional cooperation of the glycine synthase-reductase and Wood–Ljungdahl pathways for autotrophic growth of Clostridium drakei

Y Song, JS Lee, J Shin, GM Lee, S Jin… - Proceedings of the …, 2020 - National Acad Sciences
Among CO2-fixing metabolic pathways in nature, the linear Wood–Ljungdahl pathway
(WLP) in phylogenetically diverse acetate-forming acetogens comprises the most …

Synthetic biology on acetogenic bacteria for highly efficient conversion of C1 gases to biochemicals

S Jin, J Bae, Y Song, N Pearcy, J Shin, S Kang… - International journal of …, 2020 - mdpi.com
Synthesis gas, which is mainly produced from fossil fuels or biomass gasification, consists of
C1 gases such as carbon monoxide, carbon dioxide, and methane as well as hydrogen …

Engineering acetogenic bacteria for efficient one-carbon utilization

H Lee, J Bae, S Jin, S Kang, BK Cho - Frontiers in Microbiology, 2022 - frontiersin.org
C1 gases, including carbon dioxide (CO2) and carbon monoxide (CO), are major
contributors to climate crisis. Numerous studies have been conducted to fix and recycle C1 …

Adaptive Laboratory Evolution of Eubacterium limosum ATCC 8486 on Carbon Monoxide

S Kang, Y Song, S Jin, J Shin, J Bae, DR Kim… - Frontiers in …, 2020 - frontiersin.org
Acetogens are naturally capable of metabolizing carbon monoxide (CO), a component of
synthesis gas (syngas), for autotrophic growth in order to produce biomass and metabolites …

Genome Engineering of Eubacterium limosum Using Expanded Genetic Tools and the CRISPR-Cas9 System

J Shin, S Kang, Y Song, S Jin, JS Lee… - ACS Synthetic …, 2019 - ACS Publications
Eubacterium limosum is one of the important bacteria in C1 feedstock utilization as well as in
human gut microbiota. Although E. limosum has recently garnered much attention and …