Microglia are the resident macrophages of the central nervous system (CNS) acting as the
first line of defense in the brain by phagocytosing harmful pathogens and cellular debris …

Microglia are the only immune cells that permanently reside in the central nervous system
(CNS) alongside neurons and other types of glial cells. The past decade has witnessed a …

Alzheimer's disease is characterized by the histopathological presence of amyloid-β
plaques and tau-containing neurofibrillary tangles. Microglial activation is also a recognized …

The population of aged individuals is increasing worldwide and this has significant health
and socio-economic implications. Clinical and experimental studies on aging have …

Microglia are the primary immune cells of the central nervous system that help nourish and
support neurons, clear debris, and respond to foreign stimuli. Greatly impacted by their …

It has become increasingly evident that neuroinflammation plays a critical role in the
pathophysiology of Alzheimer's disease (AD) and other neurodegenerative disorders …

Translocator protein (TSPO, 18 kDa) is an evolutionary, well-preserved, and tryptophan-rich
169-amino-acid protein which localizes on the contact sites between the outer and inner …

People living with HIV face a high risk of mental illness, especially depression. We do not yet
know the precise neurobiological mechanisms underlying HIV-associated depression …

Neuroinflammation is heavily associated with various neurological diseases including
Alzheimer's disease, Parkinson's disease, multiple sclerosis, and stroke. It is strongly …

Purpose The purpose of this study was to investigate the effects of ageing, sex and body
mass index (BMI) on translocator protein (TSPO) availability in healthy subjects using …