[HTML][HTML] Surface plasmon resonance spectroscopy for characterisation of membrane protein–ligand interactions and its potential for drug discovery

SG Patching - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2014 - Elsevier
Surface plasmon resonance (SPR) spectroscopy is a rapidly developing technique for the
study of ligand binding interactions with membrane proteins, which are the major molecular …

Liposome and lipid bilayer arrays towards biosensing applications

M Bally, K Bailey, K Sugihara, D Grieshaber, J Vörös… - Small, 2010 - Wiley Online Library
Sensitive and selective biosensors for high‐throughput screening are having an increasing
impact in modern medical care. The establishment of robust protein biosensing platforms …

Surface plasmon resonance for high‐throughput ligand screening of membrane‐bound proteins

JA Maynard, NC Lindquist… - Biotechnology …, 2009 - Wiley Online Library
Technologies based on surface plasmon resonance (SPR) have allowed rapid, label‐free
characterization of protein‐protein and protein‐small molecule interactions. SPR has …

Exploring molecular-biomembrane interactions with surface plasmon resonance and dual polarization interferometry technology: expanding the spotlight onto …

TH Lee, DJ Hirst, K Kulkarni, MP Del Borgo… - Chemical …, 2018 - ACS Publications
The molecular analysis of biomolecular-membrane interactions is central to understanding
most cellular systems but has emerged as a complex technical challenge given the …

HIV-1 Tat protein-induced rapid and reversible decrease in [3H] dopamine uptake: dissociation of [3H] dopamine uptake and [3H] 2β-carbomethoxy-3-β-(4 …

J Zhu, CF Mactutus, DR Wallace, RM Booze - Journal of Pharmacology and …, 2009 - ASPET
Human immunodeficiency virus (HIV)-1 Tat protein plays a key role in the pathogenesis of
both HIV-1-associated cognitive-motor disorder and drug abuse. Dopamine (DA) transporter …

1D4: a versatile epitope tag for the purification and characterization of expressed membrane and soluble proteins

LL Molday, RS Molday - Protein Affinity Tags: Methods and Protocols, 2014 - Springer
Incorporation of short epitope tags into proteins for recognition by commercially available
monoclonal or polyclonal antibodies has greatly facilitated the detection, characterization …

Surface plasmon resonance applied to G protein-coupled receptors

S Locatelli-Hoops, AA Yeliseev… - Biomedical …, 2013 - content.iospress.com
G protein-coupled receptors (GPCR) are integral membrane proteins that transmit signals
from external stimuli to the cell interior via activation of GTP-binding proteins (G proteins) …

Polyelectrolyte microcapsule arrays: Preparation and biomedical applications

AS Sergeeva, DA Gorin, DV Volodkin - BioNanoScience, 2014 - Springer
In the need of development of versatile and flexible platforms for sensing and other
biomedical applications, micro-and nanostructured particle arrays attract strong scientific …

Control of specific attachment of proteins by adsorption of polymer layers

M Erol, H Du, S Sukhishvili - Langmuir, 2006 - ACS Publications
This study concerns the design of protein-resistant polymer adsorbed layers for the control of
surface binding of biospecific recognition entities. Polymer surface layers were prepared …

A modular approach for the construction and modification of glyco-SAMs utilizing 1, 3-dipolar cycloaddition

M Kleinert, T Winkler, A Terfort… - Organic & Biomolecular …, 2008 - pubs.rsc.org
We report the synthesis of a broad variety of functionalized molecules for assembly on gold,
allowing the formation of biologically relevant SAMs by a modular approach: either utilizing …