Chikungunya fever: epidemiology, clinical syndrome, pathogenesis and therapy

SD Thiberville, N Moyen, L Dupuis-Maguiraga… - Antiviral research, 2013 - Elsevier
Chikungunya virus (CHIKV) is the aetiological agent of the mosquito-borne disease
chikungunya fever, a debilitating arthritic disease that, during the past 7 years, has caused …

Chikungunya, a paradigm of neglected tropical disease that emerged to be a new health global risk

V Rougeron, IC Sam, M Caron, D Nkoghe… - Journal of clinical …, 2015 - Elsevier
Chikungunya virus (CHIKV) is an alphavirus of the Togaviridae family that causes chronic
and incapacitating arthralgia in human populations. Since its discovery in 1952, CHIKV was …

[HTML][HTML] Current strategies for inhibition of chikungunya infection

BB Subudhi, S Chattopadhyay, P Mishra, A Kumar - Viruses, 2018 - mdpi.com
Increasing incidences of Chikungunya virus (CHIKV) infection and co-infections with
Dengue/Zika virus have highlighted the urgency for CHIKV management. Failure in …

[HTML][HTML] Antivirals against the Chikungunya virus

V Battisti, E Urban, T Langer - Viruses, 2021 - mdpi.com
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that has re-emerged in
recent decades, causing large-scale epidemics in many parts of the world. CHIKV infection …

[HTML][HTML] Design novel dual agonists for treating type-2 diabetes by targeting peroxisome proliferator-activated receptors with core hopping approach

Y Ma, SQ Wang, WR Xu, RL Wang, KC Chou - PLoS One, 2012 - journals.plos.org
Owing to their unique functions in regulating glucose, lipid and cholesterol metabolism,
PPARs (peroxisome proliferator-activated receptors) have drawn special attention for …

[HTML][HTML] Growth in chikungunya virus-related research in ASEAN and South Asian countries from 1967 to 2022 following disease emergence: a bibliometric and …

F Sofyantoro, A Frediansyah, DS Priyono… - Globalization and …, 2023 - Springer
Abstract Background ASEAN (Association of Southeast Asian Nations) is composed of ten
Southeast Asian countries bound by socio-cultural ties that promote regional peace and …

Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus

M Bassetto, T De Burghgraeve, L Delang, A Massarotti… - Antiviral research, 2013 - Elsevier
Chikungunya virus (CHIKV) is an Arbovirus that is transmitted to humans primarily by the
mosquito species Aedes aegypti. Infection with this pathogen is often associated with fever …

[HTML][HTML] Nonstructural proteins of alphavirus—potential targets for drug development

F Abu Bakar, LFP Ng - Viruses, 2018 - mdpi.com
Alphaviruses are enveloped, positive single-stranded RNA viruses, typically transmitted by
arthropods. They often cause arthralgia or encephalitic diseases in infected humans and …

Chikungunya virus: emerging targets and new opportunities for medicinal chemistry

AA Rashad, S Mahalingam… - Journal of Medicinal …, 2014 - ACS Publications
Chikungunya virus is an emerging arbovirus that is widespread in tropical regions and is
spreading quickly to temperate climates with recent epidemics in Africa and Asia and …

[HTML][HTML] Novel alkylimidazolium ionic liquids as an antibacterial alternative to pathogens of the skin and soft tissue infections

O Forero Doria, R Castro, M Gutierrez… - Molecules, 2018 - mdpi.com
Keeping in mind the concept of green chemistry, this research aims to synthesize and
characterize new ionic liquids (ILs) derived from N-cinnamyl imidazole with different sizes of …