A review of sorting, separation and isolation of cells and microbeads for biomedical applications: microfluidic approaches

A Dalili, E Samiei, M Hoorfar - Analyst, 2019 - pubs.rsc.org
Several biomedical analyses are performed on particular types of cells present in body
samples or using functionalized microparticles. Success in such analyses depends on the …

Polymer-based MEMS electromagnetic actuator for biomedical application: A review

J Yunas, B Mulyanti, I Hamidah, M Mohd Said… - Polymers, 2020 - mdpi.com
In this study, we present a comprehensive review of polymer-based microelectromechanical
systems (MEMS) electromagnetic (EM) actuators and their implementation in the biomedical …

Viscoelasticity of blood and viscoelastic blood analogues for use in polydymethylsiloxane in vitro models of the circulatory system

L Campo-Deaño, R Dullens, DGAL Aarts, FT Pinho… - …, 2013 - pubs.aip.org
The non-Newtonian properties of blood are of great importance since they are closely
related with incident cardiovascular diseases. A good understanding of the hemodynamics …

A centrifugal-driven spiral microchannel microfiltration chip for emulsion and deformable particle sorting

Y Cai, Z Li, C Sun, X Zhao, S Wu, G Huang, S Tang… - Lab on a Chip, 2024 - pubs.rsc.org
Droplet sorting and enrichment, as a prominent field within microfluidic technology,
represent a pivotal stage in the manipulation of droplets and particles. In recent times …

Label-free separation of peripheral blood mononuclear cells from whole blood by gradient acoustic focusing

J Alsved, M Rezayati Charan, P Ohlsson… - Scientific Reports, 2024 - nature.com
Efficient techniques for separating target cells from undiluted blood are necessary for
various diagnostic and research applications. This paper presents acoustic focusing in …

High-throughput and clogging-free microfluidic filtration platform for on-chip cell separation from undiluted whole blood

Y Cheng, X Ye, Z Ma, S Xie, W Wang - Biomicrofluidics, 2016 - pubs.aip.org
Rapid separation of white blood cells from whole blood sample is often required for their
subsequent analyses of functions and phenotypes, and many advances have been made in …

Selective isolation and noninvasive analysis of circulating cancer stem cells through Raman imaging

HY Cho, MK Hossain, JH Lee, J Han, HJ Lee… - Biosensors and …, 2018 - Elsevier
Circulating cancer stem cells (CCSCs), a rare circulating tumor cell (CTC) type, recently
arose as a useful resource for monitoring and characterizing both cancers and their …

Sorting of particles using inertial focusing and laminar vortex technology: A review

A Volpe, C Gaudiuso, A Ancona - Micromachines, 2019 - mdpi.com
The capability of isolating and sorting specific types of cells is crucial in life science,
particularly for the early diagnosis of lethal diseases and monitoring of medical treatments …

Enhancement of microfluidic particle separation using cross-flow filters with hydrodynamic focusing

YY Chiu, CK Huang, YW Lu - Biomicrofluidics, 2016 - pubs.aip.org
A microfluidic chip is proposed to separate microparticles using cross-flow filtration
enhanced with hydrodynamic focusing. By exploiting a buffer flow from the side, the …

Deformability based cell sorting using microfluidic ratchets enabling phenotypic separation of leukocytes directly from whole blood

Q Guo, SP Duffy, K Matthews, E Islamzada, H Ma - Scientific reports, 2017 - nature.com
The separation of leukocytes from whole blood is a prerequisite for many biological assays.
Traditional methods require significant sample volumes and are often undesirable because …