Computational modelling for congenital heart disease: how far are we from clinical translation?

G Biglino, C Capelli, J Bruse, GM Bosi, AM Taylor… - Heart, 2017 - heart.bmj.com
Computational models of congenital heart disease (CHD) have become increasingly
sophisticated over the last 20 years. They can provide an insight into complex flow …

Detecting clinically meaningful shape clusters in medical image data: metrics analysis for hierarchical clustering applied to healthy and pathological aortic arches

JL Bruse, MA Zuluaga, A Khushnood… - IEEE Transactions …, 2017 - ieeexplore.ieee.org
Objective: Today's growing medical image databases call for novel processing tools to
structure the bulk of data and extract clinically relevant information. Unsupervised …

[HTML][HTML] How successful is successful? Aortic arch shape after successful aortic coarctation repair correlates with left ventricular function

JL Bruse, A Khushnood, K McLeod, G Biglino… - The Journal of thoracic …, 2017 - Elsevier
Objectives Even after successful aortic coarctation repair, there remains a significant
incidence of late systemic hypertension and other morbidities. Independently of residual …

Automated segmentation of 3D cine cardiovascular magnetic resonance imaging

S Tayebi Arasteh, J Romanowicz, DF Pace… - Frontiers in …, 2023 - frontiersin.org
Introduction As the life expectancy of children with congenital heart disease (CHD) is rapidly
increasing and the adult population with CHD is growing, there is an unmet need to improve …

Quantitative analysis of fetal facial morphology using 3D ultrasound and statistical shape modeling: a feasibility study

A Dall'Asta, S Schievano, JL Bruse… - American journal of …, 2017 - Elsevier
Background The antenatal detection of facial dysmorphism using 3-dimensional ultrasound
may raise the suspicion of an underlying genetic condition but infrequently leads to a …

Synthetic database of aortic morphometry and hemodynamics: overcoming medical imaging data availability

B Thamsen, P Yevtushenko… - … on Medical Imaging, 2021 - ieeexplore.ieee.org
Modeling of hemodynamics and artificial intelligence have great potential to support clinical
diagnosis and decision making. While hemodynamics modeling is extremely time-and …

Looks do matter! Aortic arch shape after hypoplastic left heart syndrome palliation correlates with cavopulmonary outcomes

JL Bruse, E Cervi, K McLeod, G Biglino… - The Annals of Thoracic …, 2017 - Elsevier
Background Aortic arch reconstruction after hypoplastic left heart syndrome (HLHS)
palliation can vary widely in shape and dimensions between patients. Arch morphology …

Statistical shape modelling to aid surgical planning: associations between surgical parameters and head shapes following spring-assisted cranioplasty

N Rodriguez-Florez, JL Bruse, A Borghi… - International journal of …, 2017 - Springer
Purpose Spring-assisted cranioplasty is performed to correct the long and narrow head
shape of children with sagittal synostosis. Such corrective surgery involves osteotomies and …

Investigating cardiac motion patterns using synthetic high-resolution 3D cardiovascular magnetic resonance images and statistical shape analysis

B Biffi, JL Bruse, MA Zuluaga, HN Ntsinjana… - Frontiers in …, 2017 - frontiersin.org
Diagnosis of ventricular dysfunction in congenital heart disease is more and more based on
medical imaging, which allows investigation of abnormal cardiac morphology and correlated …

[HTML][HTML] Automated segmentation of 3D cine cardiovascular magnetic resonance imaging

ST Arasteh, J Romanowicz, DF Pace… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Methods Ninety-nine patients with many types of CHD were imaged using a non-angulated
3D cine CMR sequence covering the whole-heart and great vessels. Automatic supervised …