The human virome: assembly, composition and host interactions
G Liang, FD Bushman - Nature Reviews Microbiology, 2021 - nature.com
The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …
known is the fact that the human body also hosts vast numbers of different viruses …
Bacteriophages and the immune system
M Popescu, JD Van Belleghem… - Annual review of …, 2021 - annualreviews.org
Bacteriophages—viruses that infect bacteria—are abundant within our bodies, but their
significance to human health is only beginning to be explored. Here, we synthesize what is …
significance to human health is only beginning to be explored. Here, we synthesize what is …
Immunogenicity of bacteriophages
K Champagne-Jorgensen, T Luong, T Darby… - Trends in …, 2023 - cell.com
Hundreds of trillions of diverse bacteriophages (phages) peacefully thrive within and on the
human body. However, whether and how phages influence their mammalian hosts is poorly …
human body. However, whether and how phages influence their mammalian hosts is poorly …
A Mammalian Cell's Guide on How to Process a Bacteriophage
L Kan, JJ Barr - Annual Review of Virology, 2023 - annualreviews.org
Bacteriophages are enigmatic entities that defy definition. Classically, they are specialist
viruses that exclusively parasitize bacterial hosts. Yet this definition becomes limiting when …
viruses that exclusively parasitize bacterial hosts. Yet this definition becomes limiting when …
The safety and efficacy of phage therapy: a systematic review of clinical and safety trials
HJ Stacey, S De Soir, JD Jones - Antibiotics, 2022 - mdpi.com
Trials of phage therapy have not consistently reported efficacy. This contrasts with promising
efficacy rates from a sizeable and compelling body of observational literature. This …
efficacy rates from a sizeable and compelling body of observational literature. This …
Bacteriophage uptake by mammalian cell layers represents a potential sink that may impact phage therapy
It is increasingly apparent that bacteriophages, viruses that infect bacteria and more
commonly referred to as simply phages, have tropisms outside their bacterial hosts. Using …
commonly referred to as simply phages, have tropisms outside their bacterial hosts. Using …
Unraveling the viral dark matter through viral metagenomics
TM Santiago-Rodriguez, EB Hollister - Frontiers in immunology, 2022 - frontiersin.org
Viruses are part of the microbiome and have essential roles in immunology, evolution,
biogeochemical cycles, health, and disease progression. Viruses influence a wide variety of …
biogeochemical cycles, health, and disease progression. Viruses influence a wide variety of …
Interactions of bacteriophages with animal and human organisms—safety issues in the light of phage therapy
M Podlacha, Ł Grabowski… - International journal of …, 2021 - mdpi.com
Bacteriophages are viruses infecting bacterial cells. Since there is a lack of specific
receptors for bacteriophages on eukaryotic cells, these viruses were for a long time …
receptors for bacteriophages on eukaryotic cells, these viruses were for a long time …
Diversity of vaginal microbiome in pregnancy: deciphering the obscurity
P Gupta, MP Singh, K Goyal - Frontiers in public health, 2020 - frontiersin.org
Human microbiota plays an indispensable role in physiology, nutrition and most
significantly, in imparting immunity. The role of microbiota has remained cryptic for years …
significantly, in imparting immunity. The role of microbiota has remained cryptic for years …
The presence of bacteriophages in the human body: good, bad or neutral?
M Łusiak-Szelachowska, B Weber-Dąbrowska… - Microorganisms, 2020 - mdpi.com
The presence of bacteriophages (phages) in the human body may impact bacterial
microbiota and modulate immunity. The role of phages in human microbiome studies and …
microbiota and modulate immunity. The role of phages in human microbiome studies and …