From classical laboratory parameters to novel biomarkers for the diagnosis of venous thrombosis

L Anghel, R Sascău, R Radu, C Stătescu - International journal of …, 2020 - mdpi.com
Venous thrombosis is a common and potentially fatal disease, because of its high morbidity
and mortality, especially in hospitalized patients. To establish the diagnosis of venous …

Metabolic reprogramming: unveiling the therapeutic potential of targeted therapies against kidney disease

S Saxena, N Dagar, V Shelke, M Lech, P Khare… - Drug Discovery …, 2023 - Elsevier
As a high-metabolic-rate organ, the kidney exhibits metabolic reprogramming (MR) in
various disease states. Given the 860.8 million cases of kidney disease worldwide in 2017 …

Apolipoprotein A4 Restricts Diet‐Induced Hepatic Steatosis via SREBF1‐Mediated Lipogenesis and Enhances IRS‐PI3K‐Akt Signaling

C Cheng, XH Liu, J He, J Gao, JT Zhou… - Molecular nutrition & …, 2022 - Wiley Online Library
Scope Hepatic steatosis and insulin resistance (IR) are risk factors for many metabolic
syndromes such as NAFLD and T2DM. ApoA4 improves glucose hemostasis by increasing …

The Roles of Fatty Acids and Apolipoproteins in the Kidneys

X Pan - Metabolites, 2022 - mdpi.com
The kidneys are organs that require energy from the metabolism of fatty acids and glucose;
several studies have shown that the kidneys are metabolically active tissues with an …

Cholesterol metabolism in chronic kidney disease: physiology, pathologic mechanisms, and treatment

X Pan - Sphingolipid Metabolism and Metabolic Disease, 2022 - Springer
High plasma levels of lipids and/or lipoproteins are risk factors for atherosclerosis,
nonalcoholic fatty liver disease (NAFLD), obesity, and diabetes. These four conditions have …

Apolipoprotein A-IV reduced metabolic inflammation in white adipose tissue by inhibiting IKK and JNK signaling in adipocytes

XH Liu, Y Zhang, L Chang, Y Wei, N Huang… - Molecular and Cellular …, 2023 - Elsevier
Abstract Apolipoprotein A-IV (ApoA-IV) plays a role in satiation and serum lipid transport. In
diet-induced obesity (DIO) C57BL/6J mice, ApoA-IV deficiency induced in ApoA-IV−/− knock …

Effects of guanidinoacetic acid supplementation on liver and breast muscle fat deposition, lipid levels, and lipid metabolism-related gene expression in ducks

H Wu, J Xie, W Peng, F Ji, J Qian, Q Shen… - Frontiers in Veterinary …, 2024 - frontiersin.org
Exogenous supplementation of guanidinoacetic acid can mechanistically regulate the
energy distribution in muscle cells. This study aimed to investigate the effects of …

Application of artificial intelligence to chronic kidney disease mineral bone disorder

ED Lederer, MM Sobh, ME Brier… - Clinical Kidney …, 2024 - academic.oup.com
The global derangement of mineral metabolism that accompanies chronic kidney disease
(CKD-MBD) is a major driver of the accelerated mortality for individuals with kidney disease …

Evaluation of cardiovascular events and progression to end-stage renal disease in patients with dyslipidemia and chronic kidney disease from the North-Eastern area …

CE Vlad, L Foia, M Pavel-Tanasa, V Toma… - … Urology and Nephrology, 2022 - Springer
Purpose The aim of this prospective cohort study was: to identify the association between
different biomarkers [proprotein convertase subtilisin/kexin 9-PCSK9, lipoprotein (a)-Lp (a) …

[PDF][PDF] Clinical-technological requirements in the rehabilitation of partially extended edentulousness complications

ME Antohe, M Madarati, NC Forna - Romanian journal of oral rehabilitation, 2021 - rjor.ro
The consequences of edentulousness are followed by major complications on the dental
support, bone and temporomandibular joint, so the rehabilitation of partial edentulousness …