Reverse vaccinology assisted design of a novel multi-epitope vaccine to target Wuchereria bancrofti cystatin: An immunoinformatics approach

NC Das, PSS Gupta, SK Panda, MK Rana… - International …, 2023 - Elsevier
Proteases are the critical mediators of immunomodulation exerted by the filarial parasites to
bypass and divert host immunity. Cystatin is a small (∼ 15 kDa) immunomodulatory filarial …

Rational design of a novel multi-epitope peptide-based vaccine against Onchocerca volvulus using transmembrane proteins

RA Shey, SM Ghogomu, DN Nebangwa… - Frontiers in Tropical …, 2022 - frontiersin.org
Almost a decade ago, it was recognized that the global elimination of onchocerciasis by
2030 will not be feasible without, at least, an effective prophylactic and/or therapeutic …

Stage-Dependent Increase of Systemic Immune Activation and CCR5+CD4+ T Cells in Filarial Driven Lymphedema in Ghana and Tanzania

AA Rahamani, S Horn, M Ritter, A Feichtner… - Pathogens, 2023 - mdpi.com
Chronic lymphedema caused by infection of Wuchereria bancrofti is a disfiguring disease
that leads to physical disability, stigmatization, and reduced quality of life. The edematous …

[PDF][PDF] Stage-Dependent Increase of Systemic Immune Activation and CCR5+CD4+ T Cells in Filarial Driven Lymphedema in Ghana and Tanzania. Pathogens 2023 …

AA Rahamani, S Horn, M Ritter, A Feichtner… - 2023 - academia.edu
Chronic lymphedema caused by infection of Wuchereria bancrofti is a disfiguring disease
that leads to physical disability, stigmatization, and reduced quality of life. The edematous …