In recent years, cancer immunotherapy based on immune checkpoint inhibitors (ICIs) has
achieved considerable success in the clinic. However, ICIs are significantly limited by the …

Omega-3 polyunsaturated fatty acids (PUFAs) are considered immunonutrients and are
commonly used in the nutritional therapy of cancer patients due to their ample biological …

Through food intake, humans obtain a variety of nutrients that are essential for growth,
cellular function, tissue development, energy, and immune defense. A special interaction …

Summary Background & Aims Sarcopenia is characterized by the progressive loss of
skeletal muscle mass and function, which reduces mobility and quality of life. Risk factors for …

Mineral oil is often used as a clinical trial placebo. Pharmaceutical-grade mineral oil consists
of a mixture of saturated hydrocarbons, with a purity and chemical structure that differs …

The incidence of differentiated thyroid cancer has been increasing in the last decades all
over the world. Such a steady growth cannot be entirely attributable to more intensive thyroid …

The HER2-positive patients occupy~ 30% of the total breast cancer patients globally where
no prevalent drugs are available to mitigate the frequent metastasis clinically except …

Chronic diseases are responsible for approximately 71% global deaths. These are
characterized by chronic low-grade inflammation and metabolic alterations.“Functional …

Cancer cachexia is a multi-organ syndrome with unintentional weight loss, sarcopenia, and
systemic inflammation. Gastrointestinal (GI) cancer patients are more susceptible to …

Breast cancer has been confirmed to have lipid disorders in the tumour microenvironment.
Peroxisome proliferator-activated receptor alpha (PPARα) is a ligand-activated …