Inositol phosphates and cell signalling

MJ Berridge, RF Irvine - Nature, 1989 - nature.com
Abstract Inositol 1, 4, 5-trisphosphate is a second messenger which regulates intracellular
calcium both by mobilizing calcium from internal stores and, perhaps indirectly, by …

[HTML][HTML] Alkaline Phosphatases: Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes

JL Millán - Purinergic signalling, 2006 - Springer
Our knowledge of the structure and function of alkaline phosphatases has increased greatly
in recent years. The crystal structure of the human placental isozyme has enabled us to …

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

DA Brown, JK Rose - Cell, 1992 - cell.com
We show that a protein with a glycosylphosphatidyl inositol (GPI) anchor can be recovered
from lysates of epithelial cells in a low density, detergent-insoluble form. Under these …

Reading a neural code

W Bialek, F Rieke, R van Steveninck… - Advances in neural …, 1989 - proceedings.neurips.cc
Traditional methods of studying neural coding characterize the en (cid: 173) coding of
known stimuli in average neural responses. Organisms face nearly the opposite task …

Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I

S Takeshita, R Kikuno, K Tezuka… - Biochemical …, 1993 - portlandpress.com
A cDNA library prepared from the mouse osteoblastic cell line MC3T3-E1 was screened for
the presence of specifically expressed genes by employing a combined subtraction …

The glycosylphosphatidylinositol anchor: a complex membrane-anchoring structure for proteins

MG Paulick, CR Bertozzi - Biochemistry, 2008 - ACS Publications
Positioned at the C-terminus of many eukaryotic proteins, the glycosylphosphatidylinositol
(GPI) anchor is a posttranslational modification that anchors the modified protein in the outer …

myo-Inositol metabolism in plants

FA Loewus, PPN Murthy - Plant science, 2000 - Elsevier
The multifunctional position supplied by myo-inositol is emerging as a central feature in
plant biochemistry and physiology. In this critique, attention is drawn to metabolic aspects …

The human alkaline phosphatases: what we know and what we don't know

H Harris - Clinica chimica acta, 1990 - Elsevier
A review of the human alkaline phosphatases dealing specifically with (1) the gene loci,(2)
characterization and discrimination of the various enzymes,(3) polymorphism at the enzyme …

Shear stress induces osteogenic differentiation of human mesenchymal stem cells

G Yourek, SM McCormick, JJ Mao… - Regenerative …, 2010 - Taylor & Francis
Aim: To determine whether fluid flow-induced shear stress affects the differentiation of bone
marrow-derived human mesenchymal stem cells (hMSCs) into osteogenic cells. Materials & …

Hypophosphatasia and the role of alkaline phosphatase in skeletal mineralization

MP Whyte - Endocrine reviews, 1994 - academic.oup.com
THIS year marks the 70th anniversary of the discovery of alkaline phosphatase (ALP)(1). For
the greater part of the past seven decades there has been universal appreciation by …