Endogenous opiates and behavior: 2006
RJ Bodnar - Peptides, 2007 - Elsevier
This paper is the 29th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning 30 years of research. It summarizes papers …
the endogenous opioid system, now spanning 30 years of research. It summarizes papers …
[HTML][HTML] Active role of the central amygdala in widespread mechanical sensitization in rats with facial inflammatory pain
M Sugimoto, Y Takahashi, YK Sugimura, R Tokunaga… - Pain, 2021 - journals.lww.com
Widespread or ectopic sensitization is a hallmark symptom of chronic pain, characterized by
aberrantly enhanced pain sensitivity in multiple body regions remote from the site of original …
aberrantly enhanced pain sensitivity in multiple body regions remote from the site of original …
Palmitoylethanolamide reduces formalin-induced neuropathic-like behaviour through spinal glial/microglial phenotypical changes in mice
Palmitoylethanolamide (PEA) is an endogenous cannabinoid-like compound in the central
nervous system, which can modulate several functions in different pathological states, such …
nervous system, which can modulate several functions in different pathological states, such …
[HTML][HTML] Peripheral analgesia: Hitting pain where it hurts
JJ McDougall - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2011 - Elsevier
Pain is a complex biological phenomenon that encompasses intricate neurophysiological,
behavioural, psychosocial and affective components. Protracted or chronic pain alerts an …
behavioural, psychosocial and affective components. Protracted or chronic pain alerts an …
Systemic TAK-242 prevents intrathecal LPS evoked hyperalgesia in male, but not female mice and prevents delayed allodynia following intraplantar formalin in both …
Objective Pain resulting from local tissue injury or inflammation typically resolves with time.
Frequently, however, this pain may unexpectedly persist, becoming a pathological chronic …
Frequently, however, this pain may unexpectedly persist, becoming a pathological chronic …
Essential role of endogenous calcitonin gene‐related peptide in pain‐associated plasticity in the central amygdala
K Shinohara, AM Watabe, M Nagase… - European Journal of …, 2017 - Wiley Online Library
The role of the neuropeptide calcitonin gene‐related peptide (CGRP) is well established in
nociceptive behaviors. CGRP is highly expressed in the projection pathway from the …
nociceptive behaviors. CGRP is highly expressed in the projection pathway from the …
Formalin injection produces long-lasting hypersensitivity with characteristics of neuropathic pain
AB Salinas-Abarca, SH Avila-Rojas… - European journal of …, 2017 - Elsevier
The purpose of this study was to investigate whether 1%, 2% or 5% formalin injection
produce hypersensitivity with characteristics of the neuropathic pain induced by spinal nerve …
produce hypersensitivity with characteristics of the neuropathic pain induced by spinal nerve …
The α5 subunit containing GABAA receptors contribute to chronic pain
It has been recently proposed that a5-subunit containing GABAA receptors (a5-GABAA
receptors) that mediate tonic inhibition might be involved in pain. The purpose of this study …
receptors) that mediate tonic inhibition might be involved in pain. The purpose of this study …
Sex-specificity and estrogen-dependence of kappa opioid receptor-mediated antinociception and antihyperalgesia
KP Lawson, S Nag, AD Thompson, SS Mokha - PAIN®, 2010 - Elsevier
This investigation determined whether the activation of the kappa opioid receptor (KOR) in
the spinal cord produces estrogen-dependent, sex-specific modulation of acute and …
the spinal cord produces estrogen-dependent, sex-specific modulation of acute and …
Role of peripheral 5-HT4, 5-HT6, and 5-HT7 receptors in development and maintenance of secondary mechanical allodynia and hyperalgesia
B Godínez-Chaparro, P Barragán-Iglesias… - PAIN®, 2011 - Elsevier
The role of 5-hydroxytryptamine (5-HT) 4, 5-HT6, and 5-HT7 receptors in formalin-induced
secondary allodynia and hyperalgesia in rats was assessed. Formalin produced acute …
secondary allodynia and hyperalgesia in rats was assessed. Formalin produced acute …