Clinical trials in progressive multiple sclerosis: lessons learned and future perspectives
D Ontaneda, RJ Fox, J Chataway - The Lancet Neurology, 2015 - thelancet.com
Progressive multiple sclerosis is characterised clinically by the gradual accrual of disability
independent of relapses and can occur with disease onset (primary progressive) or can be …
independent of relapses and can occur with disease onset (primary progressive) or can be …
Optical coherence tomography (OCT) in neuro-ophthalmology
N Minakaran, ER de Carvalho, A Petzold, SH Wong - Eye, 2021 - nature.com
Optical coherence tomography (OCT) is a non-invasive medical imaging technology that is
playing an increasing role in the routine assessment and management of patients with …
playing an increasing role in the routine assessment and management of patients with …
Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study
EH Martinez-Lapiscina, S Arnow, JA Wilson… - The Lancet …, 2016 - thelancet.com
Background Most patients with multiple sclerosis without previous optic neuritis have thinner
retinal layers than healthy controls. We assessed the role of peripapillary retinal nerve fibre …
retinal layers than healthy controls. We assessed the role of peripapillary retinal nerve fibre …
Optical coherence tomography angiography enhances the detection of optic nerve damage in multiple sclerosis
Background Quantitative assessment of optic nerve damage is important in the evaluation of
optic neuritis (ON) and multiple sclerosis (MS). Objective To detect optic nerve damage …
optic neuritis (ON) and multiple sclerosis (MS). Objective To detect optic nerve damage …
The use of optical coherence tomography in neurology: a review
JS Xie, L Donaldson, E Margolin - Brain, 2022 - academic.oup.com
Optical coherence tomography is a non-invasive, cost-efficient technique that provides high-
resolution in vivo imaging of retinal tissue. The peripapillary retinal nerve fibre layer and …
resolution in vivo imaging of retinal tissue. The peripapillary retinal nerve fibre layer and …
Retinal imaging with optical coherence tomography: a biomarker in multiple sclerosis?
F Costello, JM Burton - Eye and brain, 2018 - Taylor & Francis
Multiple sclerosis (MS) is a progressive neurological disorder characterized by both
inflammatory and degenerative components that affect genetically susceptible individuals …
inflammatory and degenerative components that affect genetically susceptible individuals …
Treatment of patients with multiple sclerosis transitioning between relapsing and progressive disease
NG Dimitriou, SG Meuth, EH Martinez-Lapiscina… - CNS drugs, 2023 - Springer
Multiple sclerosis (MS) is a chronic autoimmune demyelinating and neurodegenerative
disease of the central nervous system with a wide variety of clinical phenotypes. In spite of …
disease of the central nervous system with a wide variety of clinical phenotypes. In spite of …
Peripapillary retinal nerve fibre layer as measured by optical coherence tomography is a prognostic biomarker not only for physical but also for cognitive disability …
G Bsteh, H Hegen, B Teuchner… - Multiple Sclerosis …, 2019 - journals.sagepub.com
Background: Peripapillary retinal nerve fibre layer (pRNFL) thickness is emerging as a
marker of axonal degeneration in multiple sclerosis (MS). Objective: We aimed to …
marker of axonal degeneration in multiple sclerosis (MS). Objective: We aimed to …
Retinal measurements predict 10‐year disability in multiple sclerosis
A Rothman, OC Murphy, KC Fitzgerald… - Annals of Clinical …, 2019 - Wiley Online Library
Objective Optical coherence tomography (OCT)‐derived measures of the retina correlate
with disability and cortical gray matter atrophy in multiple sclerosis (MS); however, whether …
with disability and cortical gray matter atrophy in multiple sclerosis (MS); however, whether …
Macular ganglion cell–inner plexiform layer thinning as a biomarker of disability progression in relapsing multiple sclerosis
G Bsteh, K Berek, H Hegen, P Altmann… - Multiple Sclerosis …, 2021 - journals.sagepub.com
Background: Macular ganglion cell–inner plexiform layer (mGCIPL) is an emerging
biomarker of neuroaxonal degeneration in multiple sclerosis (MS). Objective: We aimed to …
biomarker of neuroaxonal degeneration in multiple sclerosis (MS). Objective: We aimed to …