Reframing chronic pain as a disease, not a symptom: rationale and implications for pain management

DJ Clauw, MN Essex, V Pitman… - Postgraduate medicine, 2019 - Taylor & Francis
Chronic pain is a common public health problem that has a detrimental impact on patient
health, quality of life (QoL), and function, and poses a substantial socioeconomic burden …

[PDF][PDF] Fibromyalgia syndrome: under-, over-and misdiagnosis

W Häuser, P Sarzi-Puttini, MA Fitzcharles - Clin Exp Rheumatol, 2019 - researchgate.net
Fibromyalgia syndrome (FM) is an enigma. During the past three decades, with the gradual
acceptance of the validity of FM, it is variously under-, over and misdiagnosed. Evidence …

EULAR recommendations for the management of Sjögren's syndrome with topical and systemic therapies

M Ramos-Casals, P Brito-Zerón… - Annals of the …, 2020 - ard.bmj.com
The therapeutic management of Sjögren syndrome (SjS) has not changed substantially in
recent decades: treatment decisions remain challenging in clinical practice, without a …

Transcutaneous electrical nerve stimulation reduces movement‐evoked pain and fatigue: a randomized, controlled trial

DL Dailey, CGT Vance, BA Rakel… - Arthritis & …, 2020 - Wiley Online Library
Objective Fibromyalgia (FM) is characterized by pain and fatigue, particularly during
physical activity. Transcutaneous electrical nerve stimulation (TENS) activates endogenous …

Comparative efficacy of amitriptyline, duloxetine and pregabalin for treating fibromyalgia in adults: an overview with network meta-analysis

FF Alberti, MW Becker, CR Blatt, PK Ziegelmann… - Clinical …, 2022 - Springer
Abstract Treatment recommendations for fibromyalgia (FM) include a range of predominantly
pharmacological treatment options designed to ensure the maintenance of symptoms and …

[HTML][HTML] Short-term magnesium therapy alleviates moderate stress in patients with fibromyalgia: a randomized double-blind clinical trial

N Macian, C Dualé, M Voute, V Leray, M Courrent… - Nutrients, 2022 - mdpi.com
Patients suffering from fibromyalgia often report stress and pain, with both often refractory to
usual drug treatment. Magnesium supplementation seems to improve fibromyalgia …

[HTML][HTML] Is Fibromyalgia a Fashionable Diagnosis or a Medical Mystery?

G Varrassi, M Rekatsina, S Perrot, E Bouajina… - Cureus, 2023 - ncbi.nlm.nih.gov
Despite its prevalence, there is no clear-cut diagnostic path or treatment paradigm for
fibromyalgia; this can lead to a multiplicity of symptoms and comorbid conditions that …

Stem cells therapeutic effect in a reserpine-induced fibromyalgia rat model: A possible NLRP3 inflammasome modulation with neurogenesis promotion in the cerebral …

SA Mokhemer, MK Desouky, AK Abdelghany… - Life Sciences, 2023 - Elsevier
Fibromyalgia is a chronic pain syndrome with a multifactorial pathophysiology affecting 2–
8% of the population. Aims To investigate the therapeutic effects of bone marrow …

Does physical exercise improve quality of life in patients with fibromyalgia?

SM Sieczkowska, GT Vilarino, LC de Souza… - Irish Journal of Medical …, 2020 - Springer
Background To compare patients with active and inactive fibromyalgia to better understand
the impact of physical inactivity on quality of life and symptoms in these patients. Methods A …

[HTML][HTML] Pathophysiologic approach to pain therapy for complex pain entities: a narrative review

M Rekatsina, A Paladini, A Piroli, P Zis, JV Pergolizzi… - Pain and therapy, 2020 - Springer
Pain management is challenging for both clinicians and patients. In fact, pain patients are
frequently undertreated or even completely untreated. Optimal treatment is based on …