What is principal component analysis? | Nature Biotechnology Skip to main content Thank
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Once a poorly defined pathologic oddity, in recent years, gastrointestinal stromal tumor
(GIST) has emerged as a distinct oncogenetic entity that is now center stage in clinical trials …

Background Precise prediction of cancer types is vital for cancer diagnosis and therapy.
Through a predictive model, important cancer marker genes can be inferred. Several studies …

Solitary fibrous tumor (SFT) is composed of spindled to ovoid cells in a patternless
architecture with prominent stromal collagen and hemangiopericytoma-like vessels. Some …

Background Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal
tumors of the gastrointestinal tract. Neoplastic GIST cells seem to arise from a common …

Non-biological experimental variation or “batch effects" are commonly observed across
multiple batches of microarray experiments, often rendering the task of combining data from …

Characteristic patterns of gene expression measured by DNA microarrays have been used
to classify tumors into clinically relevant subgroups. In this study, we have refined the …

Recurrent chromosomal rearrangements have not been well characterized in common
carcinomas. We used a bioinformatics approach to discover candidate oncogenic …

We reconsider randomized algorithms for the low-rank approximation of SPSD matrices
such as Laplacian and kernel matrices that arise in data analysis and machine learning …

Background The exact overall incidence of sarcoma and sarcoma subtypes is not known.
The objective of the present population-based study was to determine this incidence in a …