Gram-negative neonatal sepsis in low-and lower-middle-income countries and WHO empirical antibiotic recommendations: A systematic review and meta-analysis
Background Neonatal sepsis is a significant global health issue associated with marked
regional disparities in mortality. Antimicrobial resistance (AMR) is a growing concern in …
regional disparities in mortality. Antimicrobial resistance (AMR) is a growing concern in …
Rapid detection of multiple resistance genes to last-resort antibiotics in Enterobacteriaceae pathogens by recombinase polymerase amplification combined with …
C Lu, J Wang, L Pan, X Gu, W Lu, D Chen… - Frontiers in …, 2023 - frontiersin.org
The worrying emergence of multiple resistance genes to last-resort antibiotics in food
animals and human populations throughout the food chain and relevant environments has …
animals and human populations throughout the food chain and relevant environments has …
Challenges Facing PICUs in Low-and Middle-Income Countries in the Treatment of Emerging Multidrug-Resistant Organisms: a Review and Perspective from a South …
RT Saggers, LM Mothibi, AD Irwin… - Current Infectious Disease …, 2023 - Springer
Abstract Purpose of Review Antimicrobial resistance continues to increase throughout the
world, with the impact on critically ill children in low-and middle-income paediatric intensive …
world, with the impact on critically ill children in low-and middle-income paediatric intensive …
[HTML][HTML] Development and application of rapid clinical visualization molecular diagnostic technology for Cryptococcus neoformans/C. gattii based on recombinase …
L Wang, Y Wang, F Wang, M Zhao, X Gao… - Frontiers in cellular …, 2022 - frontiersin.org
Cryptococcus neoformans (C. neoformans)/C. gattii can easily invade the human central
nervous system and cause Cryptococcal meningitis (CM). The clinical fatality rate of these …
nervous system and cause Cryptococcal meningitis (CM). The clinical fatality rate of these …
Establishment of methods for rapid detection of Prymnesium parvum by recombinase polymerase amplification combined with a lateral flow dipstick
N Luo, H Huang, H Jiang - Frontiers in Marine Science, 2022 - frontiersin.org
Prymnesium parvum is a toxic algal bloom (HAB)-forming species. The toxicity of this alga is
a result of a collection of compounds known as prymnesins. Prymnesins exert harmful …
a result of a collection of compounds known as prymnesins. Prymnesins exert harmful …
Proof-of-concept, rapid, instrument-free molecular detection of Neisseria gonorrhoeae and ciprofloxacin susceptibility
AKS Ayfan, J Macdonald, AD Irwin… - Journal of …, 2022 - academic.oup.com
Objectives To develop instrument-free point-of-care methods using recombinase
polymerase amplification (RPA) technology coupled with a simple lateral flow detection …
polymerase amplification (RPA) technology coupled with a simple lateral flow detection …
Rapid molecular detection of CMY-2, and CTX-M group 1 and 9 variants via recombinase polymerase amplification
NG Ertl, AD Irwin, J Macdonald… - JAC-Antimicrobial …, 2023 - academic.oup.com
Background Due to their prevalence worldwide, the β-lactamases CTX-M and plasmid-
mediated CMY-2 are important antimicrobial resistance enzymes in a clinical setting. While …
mediated CMY-2 are important antimicrobial resistance enzymes in a clinical setting. While …
Advances in antimicrobial resistance testing
C Zhang, L Sun, D Wang, Y Li, L Zhang, L Wang… - Advances in Clinical …, 2022 - Elsevier
Antimicrobial resistance (AMR), especially bacterial AMR, poses a global threat to public
health and has become a huge obstacle to the effective control of related infectious …
health and has become a huge obstacle to the effective control of related infectious …
Simultaneous and Visual Detection of KPC and NDM Carbapenemase‐Encoding Genes Using Asymmetric PCR and Multiplex Lateral Flow Strip
W Lai, Y Xu, L Liu, H Cao, B Yang… - Journal of Analytical …, 2023 - Wiley Online Library
Carbapenem‐resistant Enterobacteriaceae (CRE) infections constitute a threat to public
health, and KPC and NDM are the major carbapenemases of concern. Rapid diagnostic …
health, and KPC and NDM are the major carbapenemases of concern. Rapid diagnostic …
同时产碳青霉烯酶NDM-1 和NDM-5 的猪源大肠埃希氏菌的鉴定及耐药性研究
李海利， 郎利敏， 张青娴， 游一， 朱文豪， 王治方… - 生物技术 …, 2022 - biotech.aiijournal.com
为了解携带碳青霉烯酶NDM-1 及其亚型在猪场的流行情况, 对来自猪场产房仔猪腹泻病例分离
鉴定的87 株大肠杆菌进行了碳青霉烯酶NDM-1 和NDM-5 的耐药基因扩增及测序. 从87 …
鉴定的87 株大肠杆菌进行了碳青霉烯酶NDM-1 和NDM-5 的耐药基因扩增及测序. 从87 …