Transmembrane transport of small organic and inorganic molecules is one of the
cornerstones of cellular metabolism. Among transmembrane transporters, solute carrier …

The pharmaceutical sector has made considerable strides recently, emphasizing improving
drug delivery methods to increase the bioavailability of various drugs. When used as a …

Targeted drug delivery has emerged as a pivotal approach within precision medicine,
aiming to optimize therapeutic efficacy while minimizing systemic side effects. Leukocyte …

Podophyllotoxin (PPT) has attracted researchers' attention because of its ability to treat
various ailments. A series of podophyllotoxin derivatives (PPTs) have been synthesized as …

Abstract Epigallocatechin-3-gallate (EGCG) is a kind of polyphenol with various biological
activities but poor stability and bioavailability. The encapsulation of EGCG in a nano-delivery …

For more than 40 years, the epipodophyllotoxin drug etoposide is prescribed to treat cancer.
This semi-synthetic compound remains extensively used to treat advanced small-cell lung …

Bile acid-modified nanomedicine is a promising strategy to improve oral bioavailability.
However, the efficiencies of different bile acids have not been clarified. To clarify this issue …

Atorvastatin (ATV) has attracted considerable attention as a potential therapeutic agent for
cancer because it inhibits cancer cell proliferation by suppressing the mevalonate pathway …

The lack of knowledge about the absorption, distribution, metabolism, and excretion (ADME)
of vaccines makes former biopharmaceutical optimization difficult. This was shown during …

Abstract Coenzyme Q10 (CoQ10) has a wide range of nutraceutical functions and
therapeutic values, nevertheless, its biomedical application as a health product or drug is …