Heavy metal associated health hazards: An interplay of oxidative stress and signal transduction

JG Paithankar, S Saini, S Dwivedi, A Sharma… - Chemosphere, 2021 - Elsevier
Heavy metal-induced cellular and organismal toxicity have become a major health concern
in biomedical science. Indiscriminate use of heavy metals in different sectors, such as …

[HTML][HTML] Environmental behavior, human health effect, and pollution control of heavy metal (loid) s toward full life cycle processes

H Deng, Y Tu, H Wang, Z Wang, Y Li, L Chai… - Eco-Environment & …, 2022 - Elsevier
Heavy metal (loid) s (HMs) have caused serious environmental pollution and health risks.
Although the past few years have witnessed the achievements of studies on environmental …

Curcumin-loaded core-shell biopolymer nanoparticles produced by the pH-driven method: Physicochemical and release properties

Z Li, Q Lin, DJ McClements, Y Fu, H Xie, T Li, G Chen - Food Chemistry, 2021 - Elsevier
In this study, core-shell biopolymer nanoparticles were fabricated for the encapsulation and
delivery of curcumin using a pH-driven method. The influences of the coating composition …

[HTML][HTML] Molecular basis of alcohol-related gastric and colon cancer

HK Na, JY Lee - International journal of molecular sciences, 2017 - mdpi.com
Many meta-analysis, large cohort studies, and experimental studies suggest that chronic
alcohol consumption increases the risk of gastric and colon cancer. Ethanol is metabolized …

[HTML][HTML] Redox imbalance in the development of colorectal cancer

H Liu, X Liu, C Zhang, H Zhu, Q Xu, Y Bu, Y Lei - Journal of Cancer, 2017 - ncbi.nlm.nih.gov
Redox imbalance is resulted from the destruction of balance between oxidants and
antioxidants. The dominant oxidants are reactive oxygen species (ROS), which are involved …

The 9th conference on metal toxicity and carcinogenesis: the conference overview

JTF Wise, L Wang, Z Zhang, X Shi - Toxicology and applied pharmacology, 2017 - Elsevier
Heavy metals, such as arsenic, chromium, cadmium, nickel, mercury, and uranium are
known to cause many human diseases and health complications after occupational or …

[HTML][HTML] Progress and prospects of reactive oxygen species in metal carcinogenesis

L Wang, JTF Wise, Z Zhang, X Shi - Current pharmacology reports, 2016 - Springer
Carcinogenesis induced by environmental metal exposure is a major public health concern.
The exact mechanisms underlying metal carcinogenesis remain elusive. In the past few …

[HTML][HTML] Epigenetic regulation of RCAN1 expression in kidney disease and its role in podocyte injury

H Li, W Zhang, F Zhong, GC Das, Y Xie, Z Li, W Cai… - Kidney international, 2018 - Elsevier
Mounting evidence suggests that epigenetic modification is important in kidney disease
pathogenesis. To determine whether epigenetic regulation is involved in HIV-induced …

Arsenic-mediated hyperpigmentation in skin via NF-kappa B/endothelin-1 signaling in an originally developed hairless mouse model

I Yajima, MY Kumasaka, M Iida, R Oshino… - Archives of …, 2017 - Springer
Chronic exposure to arsenic is associated with various diseases in humans. Skin
hyperpigmentation is the most sensitive objective symptom for patients with arsenicosis …

环氧合酶-2 参与环境因素诱导毒性损伤的研究进展

骆冰, 何承勇, 林忠宁 - 环境与职业医学, 2016 - jeom.org
环氧合酶-2 (cyclooxygenase-2, COX-2) 是诱导型酶, 可被促炎细胞因子, 肿瘤促进剂,
有丝分裂原和生长因子等高度诱导, 参与炎症反应, 细胞增殖和凋亡等多种病理过程 …