[HTML][HTML] The cell biology of fertilization: Gamete attachment and fusion

KK Siu, VHB Serrão, A Ziyyat, JE Lee - The Journal of Cell Biology, 2021 - ncbi.nlm.nih.gov
Fertilization is defined as the union of two gametes. During fertilization, sperm and egg fuse
to form a diploid zygote to initiate prenatal development. In mammals, fertilization involves …

A frame-by-frame glance at membrane fusion mechanisms: From viral infections to fertilization

FC Azimi, TT Dean, K Minari, LGM Basso, TDR Vance… - Biomolecules, 2023 - mdpi.com
Viral entry and fertilization are distinct biological processes that share a common
mechanism: membrane fusion. In viral entry, enveloped viruses attach to the host cell …

TMEM95 is a sperm membrane protein essential for mammalian fertilization

I Lamas-Toranzo, JG Hamze, E Bianchi… - elife, 2020 - elifesciences.org
The fusion of gamete membranes during fertilization is an essential process for sexual
reproduction. Despite its importance, only three proteins are known to be indispensable for …

Differential expression of mRNA isoforms in the skeletal muscle of pigs with distinct growth and fatness profiles

TF Cardoso, R Quintanilla, A Castelló… - BMC genomics, 2018 - Springer
Background The identification of genes differentially expressed in the skeletal muscle of pigs
displaying distinct growth and fatness profiles might contribute to identify the genetic factors …

The role of sperm proteins IZUMO1 and TMEM95 in mammalian fertilization: a systematic review

M Hernández-Falcó, P Sáez-Espinosa… - International Journal of …, 2022 - mdpi.com
Gamete membrane fusion is a critical cellular event in sexual reproduction. In addition, the
generation of knockout models has provided a powerful tool for testing the functional …

Subfertility in bulls carrying a nonsense mutation in transmembrane protein 95 is due to failure to interact with the oocyte vestments

B Fernandez-Fuertes, R Laguna-Barraza… - Biology of …, 2017 - academic.oup.com
In a recent genome-wide association study, 40 Fleckvieh bulls with exceptionally poor
fertility were found to be homozygous for a nonsense mutation in the transmembrane protein …

Comparative genome-wide alternative splicing analysis of longissimus dorsi muscles between Japanese Black (Wagyu) and Chinese Red Steppes cattle

X Fang, L Xia, H Yu, W He, Z Bai, L Qin… - Frontiers in Veterinary …, 2021 - frontiersin.org
Alternative splicing is a ubiquitous regulatory mechanism in gene expression that allows a
single gene generating multiple messenger RNAs (mRNAs). Significant differences in fat …

[HTML][HTML] 可变剪接及其在畜禽育种中的研究与应用

疏泽, 王立贤, 王立刚 - 畜牧兽医学报, 2020 - html.rhhz.net
可变剪接是指个体发育或者细胞分化时有选择地越过某些外显子或某个剪接点进行变位剪接,
从而产生组织或发育阶段特异性mRNA 的过程. 通过可变剪接, 生物体可以由单个基因产生多个 …

The muscle development transcriptome landscape of ovariectomized goat

S Zhang, H Xu, X Liu, Q Yang… - Royal Society …, 2017 - royalsocietypublishing.org
In practical production, almost all rams and about 50% of ewes are used to fatten.
Researchers have proved that ewe ovariectomy could improve the productivity significantly …

Bovine pituitary homeobox 2 (PITX2): mRNA expression profiles of different alternatively spliced variants and association analyses with growth traits

S Zhang, H Xu, Z Kang, H Cai, R Dang, C Lei, H Chen… - Gene, 2018 - Elsevier
Abstract Pituitary homeobox 2 (PITX2) plays crucial roles in embryogenesis, ontogenesis,
growth, and development via the Wnt/beta-catenin and POU1F1 pathways. To better …