Zebrafish and other small laboratory fishes are emerging as important animal models for
investigating human skeletal development and diseases. In recent years, there has been a …

Purpose of Review GWAS, as a largely correlational analysis, requires in vitro or in vivo
validation. Zebrafish (Danio rerio) have many advantages for studying the genetics of …

In coral reef fish, the transition from pelagic larvae to reef-associated juveniles is a complete
metamorphosis in which coordinated physiological, morphological, and behavioural …

Microenvironmental contributions to soft tissue sarcoma progression are relatively
undefined, particularly during sarcoma onset. Use of animal models to reveal these …

By linking anatomical structure to mechanical performance we can improve our
understanding of how selection shapes morphology. Here we examined the functional …

Bone has multiple functions in animals, such as supporting the body for mobility. The
zebrafish skeleton is composed of craniofacial and axial skeletons. It shares a physiological …

Zebrafish are increasingly becoming an important model organism for studying the
pathophysiological mechanisms of human diseases and investigating how these …

Cell size is a key contributor to tissue morphogenesis. As a notable example, growth plate
hypertrophic chondrocytes use cellular biogenesis and disproportionate fluid uptake to …

Recent adaptive radiations provide evolutionary case studies, which provide the context to
parse the relationship between genomic variation and the origins of distinct phenotypes …

Proper bone development requires coordination and timing of specific morphogenetic
events, and relative shifts in these temporal processes can change morphology. Thyroid …