Manipulating the destiny of wild populations using CRISPR
Genetic biocontrol aims to suppress or modify populations of species to protect public
health, agriculture, and biodiversity. Advancements in genome engineering technologies …
health, agriculture, and biodiversity. Advancements in genome engineering technologies …
Leveraging eco-evolutionary models for gene drive risk assessment
Engineered gene drives create potential for both widespread benefits and irreversible harms
to ecosystems. CRISPR-based systems of allelic conversion have rapidly accelerated gene …
to ecosystems. CRISPR-based systems of allelic conversion have rapidly accelerated gene …
Eliminating malaria vectors with precision-guided sterile males
RA Apte, AL Smidler, JJ Pai, ML Chow, S Chen… - Proceedings of the …, 2024 - pnas.org
Controlling the principal African malaria vector, the mosquito Anopheles gambiae, is
considered essential to curtail malaria transmission. However, existing vector control …
considered essential to curtail malaria transmission. However, existing vector control …
[HTML][HTML] Eliminating malaria vectors with precision guided sterile males
AL Smidler, RA Apte, JJ Pai, ML Chow, S Chen… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Controlling the principal African malaria vector, the mosquito Anopheles gambiae, is
considered essential to curtail malaria transmission. However existing vector control …
considered essential to curtail malaria transmission. However existing vector control …
Improving risk governance strategies via learning: a comparative analysis of solar radiation modification and gene drives
Stratospheric aerosol injection (SAI) and gene drive organisms (GDOs) have been proposed
as technological responses to complex entrenched environmental challenges. They also …
as technological responses to complex entrenched environmental challenges. They also …
A framework for identifying fertility gene targets for mammalian pest control
Fertility‐targeted gene drives have been proposed as an ethical genetic approach for
managing wild populations of vertebrate pests for public health and conservation benefit …
managing wild populations of vertebrate pests for public health and conservation benefit …
[HTML][HTML] Taking stock: Is gene drive research delivering on its principles?
AJ Roberts, K Hackett, I Coche… - Gates Open …, 2024 - gatesopenresearch.org
Gene drive technology has been recognized for its potential to provide durable and cost-
effective solutions for previously intractable problems in public health, conservation, and …
effective solutions for previously intractable problems in public health, conservation, and …
To CRISPR or Not to CRISPR? Ethical Considerations in Gene-Editing Insects
modified corn has helped feed the world (Hernandes-Lopes et al.). Genetically modified
mosquitoes could help eliminate devastating diseases like malaria (Hammond and Galizi) …
mosquitoes could help eliminate devastating diseases like malaria (Hammond and Galizi) …