A nanopore-based device provides single-molecule detection and analytical capabilities
that are achieved by electrophoretically driving molecules in solution through a nano-scale …

In nanopore analytics, individual molecules pass through a single nanopore giving rise to
detectable temporary blockades in ionic pore current. Reflecting its simplicity, nanopore …

We present the use of an alternating current (AC) signal as a means to monitor the
conductance of an α-hemolysin (αHL) pore as a DNA hairpin with a polydeoxyadenosine tail …

Nanopore analysis, which is, currently, chiefly used for DNA sequencing, is also an
appealing technique for characterizing abiotic polymers. As a first step toward this goal …

Throughput and resolution of DNA sequence detection technologies employing nanometer
scale pores hinge on accurate kinetic descriptions of DNA motion in nanopores. We present …

Single nanopores attract a great deal of scientific interest as a basis for biosensors and as a
system to study the interactions and behavior of molecules in a confined volume. Tuning the …

The translocation of polynucleotides through transmembrane protein pores is a fundamental
biological process with important technological and medical relevance. The translocation …

We report on an experiment and calculations that determine the thermal motion of a voltage-
clamped single-stranded DNA-NeutrAvidin complex in a Mycobacterium smegmatis porin A …

Molecular mechanisms of the influence of flavonoids on the voltage gating of a single alpha-
hemolysin channel in planar lipid membranes are studied. It is shown that the addition of …

Although significant progress has recently been made towards realizing the goal of direct
nanopore-based DNA sequencing (Manrao et al. in Nature Biotechnology 30: 349–353 …