Inflammation and oxidative stress: the molecular connectivity between insulin resistance, obesity, and Alzheimer's disease
Type 2 diabetes (T2DM), Alzheimer's disease (AD), and insulin resistance are age‐related
conditions and increased prevalence is of public concern. Recent research has provided …
conditions and increased prevalence is of public concern. Recent research has provided …
The role of type 2 diabetes in neurodegeneration
A growing body of evidence links type-2 diabetes (T2D) with dementia and
neurodegenerative diseases such as Alzheimer's disease (AD). AD is the most common …
neurodegenerative diseases such as Alzheimer's disease (AD). AD is the most common …
Prevalence and risk of progression of preclinical Alzheimer's disease stages: a systematic review and meta-analysis
L Parnetti, E Chipi, N Salvadori, K D'Andrea… - Alzheimer's research & …, 2019 - Springer
Background Alzheimer's disease (AD) pathology begins several years before the clinical
onset. The long preclinical phase is composed of three stages according to the …
onset. The long preclinical phase is composed of three stages according to the …
2014 Update of the Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception
MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2015 - Elsevier
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …
Amyloid-β and tau pathologies relate to distinctive brain dysconnectomics in preclinical autosomal-dominant Alzheimer's disease
E Guzmán-Vélez, I Diez… - Proceedings of the …, 2022 - National Acad Sciences
The human brain is composed of functional networks that have a modular topology, where
brain regions are organized into communities that form internally dense (segregated) and …
brain regions are organized into communities that form internally dense (segregated) and …
Early versus late MCI: Improved MCI staging using a neuropsychological approach
EC Edmonds, CR McDonald, A Marshall… - Alzheimer's & …, 2019 - Elsevier
Abstract Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) separates
“early” and “late” mild cognitive impairment (MCI) based on a single memory test. We …
“early” and “late” mild cognitive impairment (MCI) based on a single memory test. We …
Florbetapir F 18 amyloid PET and 36-month cognitive decline: a prospective multicenter study
PM Doraiswamy, RA Sperling, K Johnson… - Molecular …, 2014 - nature.com
This study was designed to evaluate whether subjects with amyloid beta (Aβ) pathology,
detected using florbetapir positron emission tomorgraphy (PET), demonstrated greater …
detected using florbetapir positron emission tomorgraphy (PET), demonstrated greater …
The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI)
Objective: Our goal was to evaluate the association of APOE with amyloid deposition,
cerebrospinal fluid levels (CSF) of Aβ, tau, and p-tau, brain atrophy, cognition and cognitive …
cerebrospinal fluid levels (CSF) of Aβ, tau, and p-tau, brain atrophy, cognition and cognitive …
Cognitive correlates of basal forebrain atrophy and associated cortical hypometabolism in mild cognitive impairment
Degeneration of basal forebrain (BF) cholinergic nuclei is associated with cognitive decline,
and this effect is believed to be mediated by neuronal dysfunction in the denervated cortical …
and this effect is believed to be mediated by neuronal dysfunction in the denervated cortical …
Multi-modal feature selection with feature correlation and feature structure fusion for MCI and AD classification
Z Jiao, S Chen, H Shi, J Xu - Brain Sciences, 2022 - mdpi.com
Feature selection for multiple types of data has been widely applied in mild cognitive
impairment (MCI) and Alzheimer's disease (AD) classification research. Combining multi …
impairment (MCI) and Alzheimer's disease (AD) classification research. Combining multi …