Mechanisms and therapeutic prospects of diabetic cardiomyopathy through the inflammatory response
N Kaur, Y Guan, R Raja, A Ruiz-Velasco… - Frontiers in …, 2021 - frontiersin.org
The incidence of heart failure (HF) continues to increase rapidly in patients with diabetes. It
is marked by myocardial remodeling, including fibrosis, hypertrophy, and cell death, leading …
is marked by myocardial remodeling, including fibrosis, hypertrophy, and cell death, leading …
The role of MSC therapy in attenuating the damaging effects of the cytokine storm induced by COVID-19 on the heart and cardiovascular system
GM Ellison-Hughes, L Colley, KA O'Brien… - Frontiers in …, 2020 - frontiersin.org
The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
that causes coronavirus disease 2019 (COVID-19) has led to 47 m infected cases and 1. 2 m …
that causes coronavirus disease 2019 (COVID-19) has led to 47 m infected cases and 1. 2 m …
Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative …
Single cell RNA sequencing studies identified novel neurodegeneration-associated
microglial (MGnD/DAM) subtypes activated around cerebral amyloid plaques. Micro-RNA …
microglial (MGnD/DAM) subtypes activated around cerebral amyloid plaques. Micro-RNA …
Sustained activation of NF-κB through constitutively active IKKβ leads to senescence bypass in murine dermal fibroblasts
M Harada, K Su-Harada, T Kimura, K Ono, N Ashida - Cell Cycle, 2024 - Taylor & Francis
Although the transcription factor nuclear factor κB (NF-κB) plays a central role in the
regulation of senescence-associated secretory phenotype (SASP) acquisition, our …
regulation of senescence-associated secretory phenotype (SASP) acquisition, our …
PI3K signalling at the intersection of cardio-oncology networks: cardiac safety in the era of AI
M Ezeani, S Prabhu - Cellular and Molecular Life Sciences, 2022 - Springer
Class I phosphoinositide 3-kinases (PI3Ks) are a family of lipid kinases. They are super
elevated in many human cancer types and exert their main cellular functions by activating …
elevated in many human cancer types and exert their main cellular functions by activating …
The use of Droplet-On-Demand Printing Technologies for Healthcare Applications
TD Pollard - 2024 - discovery.ucl.ac.uk
The efficacy of current healthcare treatments is low. Orally administered drugs lead to
systemic drug distribution, while many diseases are only treated reactively. An alternative …
systemic drug distribution, while many diseases are only treated reactively. An alternative …
Insulin sensitivity during sepsis induced by peritoneal contamination and infection in transgenic SIRT1-overexpressing mice
M Bley - 2022 - db-thueringen.de
Sepsis is a severe complication of infection linked to high mortality by organ failure such as
septic cardiomyopathy. As a result of inflammation, insulin resistance can be found during …
septic cardiomyopathy. As a result of inflammation, insulin resistance can be found during …