Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …

Nuclear bodies are RNA and protein-rich, membraneless organelles that play important
roles in gene regulation. The largest and most well-known nuclear body is the nucleolus, an …

Multicomponent systems are ubiquitous in nature and industry. While the physics of few-
component liquid mixtures (ie, binary and ternary ones) is well-understood and routinely …

When micron-scale compositional heterogeneity develops in membranes, the distribution of
lipids on one face of the membrane strongly affects the distribution on the other. Specifically …

The plasma membrane is a highly complex multicomponent system that is central to the
functioning of cells. Cholesterol, a key lipid component of the plasma membrane, promotes …

A simulation method for the dynamics of inhomogeneous lipid bilayer membranes is
presented. The membrane is treated using stochastic Saffman-Delbrück hydrodynamics …

We study diffusion coefficients of liquid domains by explicitly taking into account the two-
layered structure called leaflets of the bilayer membrane. In general, the velocity fields …

The kinetics of registration of lipid domains in the apposing leaflets of symmetric bilayer
membranes is investigated via systematic dissipative particle dynamics simulations. The …

Due to a thermodynamic coupling between the two leaflets comprising a lipid bilayer,
compositional lipid domains residing within opposing leaflets are often found in registry. If …

In this dissertation, we both analytically and computationally investigate several dynamic
problems related to compositional lipid microdomains in model bilayer membranes. We …