Agnostic sequencing for detection of viral pathogens

NPG Gauthier, SD Chorlton, M Krajden… - Clinical microbiology …, 2023 - Am Soc Microbiol
The advent of next-generation sequencing (NGS) technologies has expanded our ability to
detect and analyze microbial genomes and has yielded novel molecular approaches for …

Genomics for emerging pathogen identification and monitoring: Prospects and obstacles

V Vashisht, A Vashisht, AK Mondal, J Farmaha… - …, 2023 - mdpi.com
Emerging infectious diseases (EIDs) pose an increasingly significant global burden, driven
by urbanization, population explosion, global travel, changes in human behavior, and …

[HTML][HTML] First report and genetic characterization of the highly pathogenic avian influenza A (H5N1) virus in Cabot's tern (Thalasseus acuflavidus), Brazil

D Reischak, AV Rivetti Jr, JNP Otaka… - Veterinary and Animal …, 2023 - Elsevier
Abstract In 2021, the H5N1 virus lineage 2.3. 4.4 b spread to the Americas, causing high
mortality in wild and domestic avian populations. South American countries along the Pacific …

[HTML][HTML] Long-term monitoring of SARS-CoV-2 variants in wastewater using a coordinated workflow of droplet digital PCR and nanopore sequencing

K Vigil, N D'Souza, J Bazner, FMA Cedraz, S Fisch… - Water Research, 2024 - Elsevier
Quantitative polymerase chain reaction (PCR) and genome sequencing are important
methods for wastewater surveillance of severe acute respiratory syndrome coronavirus 2 …

BugSplit enables genome-resolved metagenomics through highly accurate taxonomic binning of metagenomic assemblies

I Chandrakumar, NPG Gauthier, C Nelson… - Communications …, 2022 - nature.com
A large gap remains between sequencing a microbial community and characterizing all of
the organisms inside of it. Here we develop a novel method to taxonomically bin …

Diversity of human enterovirus co-circulations in five kindergartens in Bangkok between July 2019 and January 2020

P Sittikul, EM Batty, P Yodsawat, J Nuanpirom… - Viruses, 2023 - mdpi.com
Human enterovirus causes various clinical manifestations in the form of rashes, febrile
illness, flu-like illness, uveitis, hand–foot–mouth disease (HFMD), herpangina, meningitis …

The application status of sequencing technology in global respiratory infectious disease diagnosis

J Chen, Z Qin, Z Jia - Infection, 2024 - Springer
Next-generation sequencing (NGS) has revolutionized clinical microbiology, particularly in
diagnosing respiratory infectious diseases and conducting epidemiological investigations …

[HTML][HTML] Recovery of complete genome sequences of Crimean-Congo haemorrhagic fever virus (CCHFV) directly from clinical samples: A comparative study between …

J D'Addiego, N Wand, B Afrough, T Fletcher… - Journal of Virological …, 2024 - Elsevier
Crimean-Congo haemorrhagic fever (CCHF) is the most prevalent human tick-borne viral
disease, endemic to the Balkans, Africa, Middle East and Asia. There are currently no …

SARS-CoV-2 and variants: Alternative therapies to avert COVID-19

B Singh, G Mal, R Sharma, G Jairath, D Gopinath… - Metagenomics, 2025 - Elsevier
Coronaviruses (CoVs) are highly contagious viruses in humans, pets, and wild animals.
SARS-CoV-2, a novel CoV caused severe pandemic known as COVID-19. Mutations in the …

[HTML][HTML] Genomic Evolution of the SARS-CoV-2 Omicron Variant in Córdoba, Argentina (2021–2022): Analysis of Uncommon and Prevalent Spike Mutations

NB Olivero, VE Zappia, P Gargantini… - Viruses, 2024 - mdpi.com
Understanding the evolutionary patterns and geographic spread of SARS-CoV-2 variants,
particularly Omicron, is essential for effective public health responses. This study focused on …