B-cell receptor immunoglobulin stereotypy in chronic lymphocytic leukemia: Key to understanding disease biology and stratifying patients

A Agathangelidis, T Chatzikonstantinou… - Seminars in …, 2024 - Elsevier
Sequence convergence, otherwise stereotypy, of B-cell receptor immunoglobulin (BcR IG)
from unrelated patients is a distinctive feature of the IG gene repertoire in chronic …

[HTML][HTML] Persistent B-Cell Stimulation or B-Cell Repertoire Anomalies? The Dilemma of the Origin of Chronic Lymphocytic Leukemia (CLL)

M Ferrarini, D Bagnara, F Ghiotto, F Fais - Lymphatics, 2024 - mdpi.com
Lymphatics | Free Full-Text | Persistent B-Cell Stimulation or B-Cell Repertoire Anomalies?
The Dilemma of the Origin of CLL Previous Article in Journal Prevalence and Quality of Life …

EXPRESSION OF IMMUNOGLOBULIN LIGHT CHAIN GENES IN STEREOTYPED CASES FROM UKRAINIAN COHORT OF CHRONIC LYMPHOCYTIC LEUKEMIA …

I Abramenko, N Bilous, Z Martina… - Experimental …, 2024 - exp-oncology.com.ua
Background. Analysis of immunoglobulin heavy chain gene (IGHV) rearrangements
expressed in chronic lymphocytic leukemia (CLL) cells has provided insights into the B-cell …

Evidence that chronic lymphocytic leukemia arises from a multiclonal selection process

D Bagnara, N Cardente, S Vergani, S Kasar… - 2024 - researchsquare.com
Although chronic lymphocytic leukemia (CLL) is diagnosed by identifying in a patient's blood
a B-cell clone that exceeds 5x10 6/µL, additional clones have on occasion been identified …

Immunoglobulin Heavy Chain Gene Mutations in Chronic Lymphoid Leukemia

A Dalyan, M Ozaslan - The Eurasia Proceedings of Health, Environment …, 2024 - ephels.net
Chronic lymphoid leukemia (CLL) is the most common type of leukemia in adults in western
countries and is a clinically and genetically heterogeneous disease. Although the …

Stereotyped B-Cell Receptor Immunoglobulins in B-Cell Lymphomas

A Agathangelidis, A Roussos, K Kardamiliotis… - … : Methods and Protocols, 2024 - Springer
Thorough examination of clonotypic B-cell receptor immunoglobulin (BcR IG) gene
rearrangement sequences in patients with mature B-cell malignancies has revealed …