Ultra-high field proton MR spectroscopy in early-stage amyotrophic lateral sclerosis

I Cheong, M Marjańska, DK Deelchand… - Neurochemical …, 2017 - Springer
A major hurdle in the development of effective treatments for amyotrophic lateral sclerosis
(ALS) has been the lack of robust biomarkers for use as clinical trial endpoints …

Noninvasive Assessment of Neurochemical Biomarkers in Humans with Amyotrophic Lateral Sclerosis: Correlates of Clinical Heterogeneity

I Cheong - 2018 - conservancy.umn.edu
Noninvasive neuroimaging techniques can provide objective measures of disease status
that are critical for the development of neurological disease therapies. They can also unlock …