[HTML][HTML] Cinnoline scaffold—a molecular heart of medicinal chemistry?

M Szumilak, A Stanczak - Molecules, 2019 - mdpi.com
The cinnoline nucleus is a very important bicyclic heterocycle that is used as the structural
subunit of many compounds with interesting pharmaceutical properties. Cinnoline …

[HTML][HTML] Synthesis and Properties of 6-Aryl-4-azidocinnolines and 6-Aryl-4-(1,2,3-1H-triazol-1-yl)cinnolines

NA Danilkina, NS Bukhtiiarova, AI Govdi, AA Vasileva… - Molecules, 2019 - mdpi.com
An efficient approach towards the synthesis of 6-aryl-4-azidocinnolines was developed with
the aim of exploring the photophysical properties of 6-aryl-4-azidocinnolines and their click …

Design, synthesis, and molecular docking study of novel cinnoline derivatives as potential inhibitors of tubulin polymerization

EM Mahmoud, M Shongwe, ES Moghadam… - … für Naturforschung C, 2023 - degruyter.com
The preparation of a novel 4-methylbenzo [h] cinnolines entity via a three-step synthetic
protocol is described. Cyclization of the naphthylamidrazones, in the presence of …

New Synthetic Route to Cinnoline Derivatives and Their Microbiological Activity

H Lettreuch, M Khodja, H Boutoumi - Russian Journal of Organic …, 2020 - Springer
New cinnoline derivatives have been synthesized by reductive cyclization of hydrazones
obtained by condensation of various 2-nitrophenylhydrazine derivatives with methyl …