[HTML][HTML] Roles and mechanisms of exosomal non-coding RNAs in human health and diseases

C Li, YQ Ni, H Xu, QY Xiang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …

Strategic vision for improving human health at The Forefront of Genomics

ED Green, C Gunter, LG Biesecker, V Di Francesco… - Nature, 2020 - nature.com
Starting with the launch of the Human Genome Project three decades ago, and continuing
after its completion in 2003, genomics has progressively come to have a central and …

[HTML][HTML] New insight towards development of paclitaxel and docetaxel resistance in cancer cells: EMT as a novel molecular mechanism and therapeutic possibilities

M Ashrafizadeh, S Mirzaei, F Hashemi, A Zarrabi… - Biomedicine & …, 2021 - Elsevier
Epithelial-to-mesenchymal transition (EMT) mechanism is responsible for metastasis and
migration of cancer cells to neighboring cells and tissues. Morphologically, epithelial cells …

Circular RNAs as emerging players in cervical cancer tumorigenesis; a review to roles and biomarker potentials

S Najafi - International Journal of Biological Macromolecules, 2022 - Elsevier
Cervical cancer is the most lethal gynecological cancer among women worldwide. Most of
the patients are diagnosed at the advanced stages due to late diagnosis and lack of …

Long non-coding RNAs (lncRNAs); roles in tumorigenesis and potentials as biomarkers in cancer diagnosis

S Najafi, SH Khatami, M Khorsand, Z Jamali… - Experimental cell …, 2022 - Elsevier
New research has indicated that long non-coding RNAs (lncRNAs) play critical roles in a
broad range of biological processes, including the pathogenesis of many complex human …

[HTML][HTML] MicroRNAs and apoptosis in colorectal cancer

H Wang - International journal of molecular sciences, 2020 - mdpi.com
Colorectal cancer (CRC) is the third leading cause of cancer death in the world, and its
incidence is rising in developing countries. Treatment with 5-Fluorouracil (5-FU) is known to …

[HTML][HTML] Epitranscriptomics and epiproteomics in cancer drug resistance: therapeutic implications

H Song, D Liu, S Dong, L Zeng, Z Wu, P Zhao… - Signal transduction and …, 2020 - nature.com
Drug resistance is a major hurdle in cancer treatment and a key cause of poor prognosis.
Epitranscriptomics and epiproteomics are crucial in cell proliferation, migration, invasion …

[HTML][HTML] Long non-coding RNAs regulated NF-κB signaling in cancer metastasis: Micromanaging by not so small non-coding RNAs

S Ahmad, M Abbas, MF Ullah, MH Aziz… - Seminars in cancer …, 2022 - Elsevier
Cancer metastasis is a major reason for the cancer-associated deaths and a role of long non-
coding RNAs (lncRNAs) in cancer metastasis is increasingly being realized. Among the …

[HTML][HTML] Targeting miRNA by CRISPR/Cas in cancer: advantages and challenges

BM Hussen, MF Rasul, SR Abdullah, HJ Hidayat… - Military Medical …, 2023 - Springer
Clustered regulatory interspaced short palindromic repeats (CRISPR) has changed
biomedical research and provided entirely new models to analyze every aspect of …

[HTML][HTML] Mechanistic actions of microRNAs in diabetic wound healing

M Petkovic, AE Sørensen, EC Leal, E Carvalho… - Cells, 2020 - mdpi.com
Wound healing is a complex biological process that is impaired under diabetes conditions.
Chronic non-healing wounds in diabetes are some of the most expensive healthcare …