Synthetic genomics is the construction of viruses, bacteria, and eukaryotic cells with
synthetic genomes. It involves two basic processes: synthesis of complete genomes or …

In vitro transcribed (IVT) mRNA has recently come into focus as a potential new drug class to
deliver genetic information. Such synthetic mRNA can be engineered to transiently express …

Ten years ago, a correspondence [1, 2], signed by more than 70 championed 'A global
initiative on sharing avian flu data'(GISAID)[3], leading to the GISAID Initiative in 2008. What …

Two doses of the BNT162b2 mRNA vaccine are highly effective against SARS-CoV-2. Here,
we tested the antibody neutralization against Omicron SARS-CoV-2 after 2 and 3 doses of …

Since its introduction in 1982, biopharmaceutical drugs have revolutionized the treatment of
a broad spectrum of diseases and are increasingly used in nearly all branches of medicine …

The chemical synthesis of DNA oligonucleotides and their assembly into synthons, genes,
circuits, and even entire genomes by gene synthesis methods has become an enabling …

For over 60 years, the synthetic production of new DNA sequences has helped researchers
understand and engineer biology. Here we summarize methods and caveats for the de novo …

INTRODUCTION In 1984, the simplest cells capable of autonomous growth, the
mycoplasmas, were proposed as models for understanding the basic principles of life. In …

In the last century, vaccination has been the most effective medical intervention to reduce
death and morbidity caused by infectious diseases. It is believed that vaccines save at least …

Although antiviral drugs and vaccines have reduced the economic and healthcare burdens
of influenza, influenza epidemics continue to take a toll. Over the past decade, research on …