Enhanced long-term survival rates of young women with cancer and advances in
reproductive medicine and cryobiology have culminated in an increased interest in fertility …

BACKGROUND Advanced maternal age is associated with reduced fertility and adverse
pregnancy outcomes. This review details recent developments in our understanding of the …

STUDY QUESTION Can complete oocyte development be achieved from human ovarian
tissue containing primordial/unilaminar follicles and grown in vitro in a multi-step culture to …

Patients preparing to undergo gonadotoxic medical therapy, radiation therapy, or
gonadectomy should be provided with prompt counseling regarding available options for …

Study Question What progress has been made in fertility preservation (FP) over the last
decade? Summary Answer FP techniques have been widely adopted over the last decade …

The removal and cryostorage of ovarian cortical biopsies is now offered as a fertility
preservation option for young women. The only available option to restore fertility using this …

STUDY QUESTION Can a reconstructed ovary using decellularized human ovarian tissue
(DCT) support survival of pre-antral stage follicles? SUMMARY ANSWER We have …

Ovarian tissue cryopreservation is an option to preserve reproductive potential in patients
who must urgently undergo aggressive chemotherapy and/or radiotherapy or who have …

Patients preparing to undergo gonadotoxic medical therapy or radiation therapy or
gonadectomy should be provided with prompt counseling regarding available options for …

Improved survival rates among reproductive‐age females diagnosed with cancer have
increased the focus on long‐term quality of life, including maintenance of the ability to …