[HTML][HTML] Mechanisms of macular edema: beyond the surface

A Daruich, A Matet, A Moulin, L Kowalczuk… - Progress in retinal and …, 2018 - Elsevier
Macular edema consists of intra-or subretinal fluid accumulation in the macular region. It
occurs during the course of numerous retinal disorders and can cause severe impairment of …

[HTML][HTML] Macular telangiectasia type 2

PC Issa, MC Gillies, EY Chew, AC Bird… - Progress in retinal and …, 2013 - Elsevier
Macular telangiectasia type 2 is a bilateral disease of unknown cause with characteristic
alterations of the macular capillary network and neurosensory atrophy. Its prevalence may …

Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1

JS Joyal, Y Sun, ML Gantner, Z Shao, LP Evans… - Nature medicine, 2016 - nature.com
Tissues with high metabolic rates often use lipids, as well as glucose, for energy, conferring
a survival advantage during feast and famine. Current dogma suggests that high-energy …

Retinal vascular layers in macular telangiectasia type 2 imaged by optical coherence tomographic angiography

RF Spaide, JM Klancnik, MJ Cooney - JAMA ophthalmology, 2015 - jamanetwork.com
Importance Macular telangiectasia type 2 (MacTel 2) is a rare disease in which
abnormalities of the retinal vasculature play a key role. The vascular abnormalities are …

Conditional Müller cell ablation causes independent neuronal and vascular pathologies in a novel transgenic model

W Shen, M Fruttiger, L Zhu, SH Chung… - Journal of …, 2012 - Soc Neuroscience
Müller cells are the major glia of the retina that serve numerous functions essential to retinal
homeostasis, yet the contribution of Müller glial dysfunction to retinal diseases remains …

Perifoveal Müller cell depletion in a case of macular telangiectasia type 2

MB Powner, MC Gillies, M Tretiach, A Scott… - Ophthalmology, 2010 - Elsevier
PURPOSE: To assess the histopathologic changes in a postmortem sample derived from an
eye donor with macular telangiectasia (MacTel) type 2 to gain further insight into the cause …

Loss of Müller's cells and photoreceptors in macular telangiectasia type 2

MB Powner, MC Gillies, M Zhu, K Vevis, AP Hunyor… - Ophthalmology, 2013 - Elsevier
Purpose To correlate postmortem histology from a patient with macular telangiectasia
(MacTel) type 2 with previously recorded clinical imaging data. Design Observational …

Retinal energy demands control vascular supply of the retina in development and disease: The role of neuronal lipid and glucose metabolism

JS Joyal, ML Gantner, LEH Smith - Progress in retinal and eye research, 2018 - Elsevier
Neuronal energy demands are met by a tightly coupled and adaptive vascular network that
supplies nutrients and oxygen. The retina is one of the highest energy-consuming organs …

Swept-source OCT angiography of the retinal vasculature using intensity differentiation-based optical microangiography algorithms

Y Huang, Q Zhang, MR Thorell, L An… - … Surgery, Lasers and …, 2014 - journals.healio.com
BACKGROUND AND OBJECTIVE: To demonstrate the feasibility of using a 1,050-nm swept-
source optical coherence tomography (SS-OCT) system to achieve noninvasive retinal …

The application of optical coherence tomography angiography in retinal diseases

K Sambhav, S Grover, KV Chalam - Survey of Ophthalmology, 2017 - Elsevier
Optical coherence tomography angiography (OCTA) is a new, noninvasive imaging
technique that generates real-time volumetric data on chorioretinal vasculature and its flow …