Background The peritoneum is a bilayer serous membrane that lines the abdominal cavity.
We present a review of peritoneal structure and physiology, with a focus on the peritoneal …

Chronic inflammation is an underlying factor linking obesity with insulin resistance. Diet-
induced obesity promotes an increase in circulating levels of inflammatory monocytes and …

ABSTRACT A recent hypothesis postulates that sepsis moves through different phases, with
periods of enhanced inflammation alternating with periods of immune suppression. In this …

Invasive fungal infections are life-threatening, and neutrophils are vital cells of the innate
immune system that defend against them. The role of LTA4H-LTB4-BLT1 axis in regulation …

Secondary peritonitis continues to cause high morbidity and mortality despite improvements
in medical and surgical therapy. This review combines data from published literature …

Alcoholic liver disease (ALD) is a major public health problem in the United States and
women are known to be more susceptible to ALD. However, the precise mechanism for …

Chronic inflammation contributes toward the pathogenesis of numerous diseases including,
but not limited to, obesity, autoimmunity, cardiovascular diseases, and cancers. The …

Activation of toll‐like receptors (TLRs) and polymorphonuclear leukocyte (PMN)
accumulation at infection sites are critical events of host defense. The involvement of …

Inflammation and infection are key promoters of colon cancer but the molecular interplay
between these events is largely unknown. Mice deficient in leukotriene B4 receptor1 (BLT1) …

Type 1 diabetes enhances susceptibility to infection and favors the sepsis development. In
addition, diabetic mice produced higher levels of histamine in several tissues and in the …