This review describes the diffusion model for light transport in tissues and the medical
applications of diffuse light. Diffuse optics is particularly useful for measurement of tissue …

The use of near-infrared (NIR) light to interrogate deep tissues has enormous potential for
molecular-based imaging when coupled with NIR excitable dyes. More than a decade has …

While some materials are opaque because they strongly absorb visible light, others, such as
foam, white paint, biological tissue and milk, are opaque because photons traveling within …

We present three-dimensional (3D) in vivo images of human breast cancer based on
fluorescence diffuse optical tomography (FDOT). To our knowledge, this work represents the …

We have measured the bulk optical properties of healthy female breast tissues in vivo in the
parallel plate, transmission geometry. Fifty-two volunteers were measured. Blood volume …

We present images of heterogeneous turbid media derived from measurements of diffuse
photon-density waves traveling through highly scattering tissue phantoms. To our …

57 ABSTRACT A System and method non-invasive biomedical optical imag ing and
spectroscopy with low-level light is described. The technique consists of a modulated light …

We investigate the uptake of a nontargeted contrast agent by breast tumors using a
continuous wave diffuse optical tomography apparatus. The instrument operates in the near …

The lifetime of a fluorophore generally varies in different environments, making the molecule
a sensitive indicator of tissue oxygenation, pH, and glucose. However, lifetime …

We present a steady-state radially resolved diffuse reflectance spectrometer capable of
measuring the absorption and transport scattering spectra of tissue-simulating phantoms …