Determination of lipoic acid in biological samples
K Borowczyk, M Krawczyk, P Kubalczyk, G Chwatko - Bioanalysis, 2015 - Taylor & Francis
α-Lipoic acid (LA) is a unique antioxidant that is not only effective in affording protection
against oxidative stress but also plays an essential role in metabolic processes of all living …
against oxidative stress but also plays an essential role in metabolic processes of all living …
Silver anchored g-C3N4/CNT nanocomposites modified glassy carbon electrode for the detection of α-lipoic acid in pharmaceutical products
J Amarnath, S Meenakshi, J Kalaiyarasi… - Inorganic Chemistry …, 2024 - Elsevier
Abstract AgNPs anchored gC 3 N 4/CNT nanocomposites have been exploited for the
electrochemical sensitive determination of α-lipoic acid (α-LA) in pharmaceutical tablets. The …
electrochemical sensitive determination of α-lipoic acid (α-LA) in pharmaceutical tablets. The …
Determination of lipoic acid in human plasma by HPLC-ECD using liquid–liquid and solid-phase extraction: Method development, validation and optimization of …
A rapid, inexpensive, sensitive and specific HPLC-ECD method for the determination of
lipoic acid in human plasma was developed and validated over the linearity range of 0.001 …
lipoic acid in human plasma was developed and validated over the linearity range of 0.001 …
Distribution study of orally administered lipoic acid in rat brain tissues
HT Chng, LS New, AH Neo, CW Goh, ER Browne… - Brain research, 2009 - Elsevier
Lipoic acid (LA), an essential cofactor for mitochondrial enzymes and a natural antioxidant,
has been explored for the treatment of Alzheimer's disease. However, lipoic acid distribution …
has been explored for the treatment of Alzheimer's disease. However, lipoic acid distribution …
Reverse-phase liquid chromatographic determination of α-lipoic acid in dietary supplements using a boron-doped diamond electrode
W Siangproh, P Rattanarat, O Chailapakul - Journal of Chromatography A, 2010 - Elsevier
A fast liquid chromatographic separation, coupled with sensitive and straightforward
detection using a boron-doped diamond (BDD) electrode, was developed and validated for …
detection using a boron-doped diamond (BDD) electrode, was developed and validated for …
Are analysts doing method validation in liquid chromatography?
MJ Ruiz-Angel, MC García-Alvarez-Coque… - … of Chromatography A, 2014 - Elsevier
Method validation is being applied in the reported analytical methods for decades. Even
before this protocol was defined, authors already somehow validated their methods without …
before this protocol was defined, authors already somehow validated their methods without …
α-Lipoic acid in dietary supplements: Development and comparison of HPLC-CEAD and HPLC-ESI-MS methods
AI Durrani, H Schwartz, W Schmid, G Sontag - Journal of pharmaceutical …, 2007 - Elsevier
α-Lipoic acid is an antioxidant used both in the prevention and treatment of various oxidative
stress related diseases. It is an important constituent of some dietary supplements and can …
stress related diseases. It is an important constituent of some dietary supplements and can …
In situ one-pot synthesis of chitosan@ P, N-CPDs as a ratiometric scatter up-conversion sensor for α-lipoic acid
AA Abdella, SF Hammad - Microchemical Journal, 2024 - Elsevier
The rapid sensitive determination of α-lipoic acid (ALA) is essential for monitoring biological
functions. Nevertheless, the lack of chromophore and its occurrence in complex biological …
functions. Nevertheless, the lack of chromophore and its occurrence in complex biological …
The in vivo study on antioxidant activity of wendan decoction in treating hyperlipidemia: a pharmacokinetic-pharmacodynamic (PK-PD) model
N Xu, M Ijaz, Y Shu, P Wang, L Ma, P Wang… - Frontiers in …, 2024 - frontiersin.org
Background: Wendan Decoction (WDD) is a six-herb Chinese medicine recipe that was first
mentioned in about 652 AD. It is frequently used to treat hyperlipidemic patients' clinical …
mentioned in about 652 AD. It is frequently used to treat hyperlipidemic patients' clinical …
A sensitive LC/MS/MS bioanalysis assay of orally administered lipoic acid in rat blood and brain tissue
HT Chng, LS New, AH Neo, CW Goh… - … of pharmaceutical and …, 2010 - Elsevier
A sensitive liquid chromatography tandem mass spectrometry (LC/MS/MS) bioanalytical
method was developed and validated to analyze lipoic acid (LA) in rat blood and brain …
method was developed and validated to analyze lipoic acid (LA) in rat blood and brain …