Extended criteria donors in liver transplantation

I Vodkin, A Kuo - Clinics in liver disease, 2017 - liver.theclinics.com
Mortality rates on the liver transplant waiting list are increasing. 1 The shortage of organs
has resulted in higher utilization of extended criteria donors (ECDs), with centers pushing …

Donor warm ischemia time in DCD liver transplantation—working group report from the ILTS DCD, liver preservation, and machine perfusion consensus conference

M Kalisvaart, KP Croome… - …, 2021 - journals.lww.com
Donation after circulatory death (DCD) grafts are commonly used in liver transplantation.
Attributable to the additional ischemic event during the donor warm ischemia time (DWIT) …

[HTML][HTML] Abdominal normothermic regional perfusion in controlled donation after circulatory determination of death liver transplantation: outcomes and risk factors for …

AJ Hessheimer, G de la Rosa, M Gastaca… - American Journal of …, 2022 - Elsevier
Postmortem normothermic regional perfusion (NRP) is a rising preservation strategy in
controlled donation after circulatory determination of death (cDCD). Herein, we present …

[HTML][HTML] Liver transplantation after ex vivo normothermic machine preservation: a phase 1 (first-in-man) clinical trial

R Ravikumar, W Jassem, H Mergental, N Heaton… - American Journal of …, 2016 - Elsevier
The number of donor organs suitable for liver transplantation is restricted by cold
preservation and ischemia–reperfusion injury. We present the first patients transplanted …

Cholangiocyte organoids can repair bile ducts after transplantation in the human liver

F Sampaziotis, D Muraro, OC Tysoe, S Sawiak… - Science, 2021 - science.org
Organoid technology holds great promise for regenerative medicine but has not yet been
applied to humans. We address this challenge using cholangiocyte organoids in the context …

HOPE for human liver grafts obtained from donors after cardiac death

P Dutkowski, A Schlegel, M de Oliveira, B Müllhaupt… - Journal of …, 2014 - Elsevier
Background & Aims Due to ethical rules in most countries, long ischemia times are
unavoidable prior to organ procurement of donors without a heartbeat, which can cause …

Biliary complications after liver transplantation from donation after cardiac death donors: an analysis of risk factors and long-term outcomes from a single center

DP Foley, LA Fernandez, G Leverson… - Annals of …, 2011 - journals.lww.com
Objective: This study evaluates the long-term outcomes, biliary complication rates, and risk
factors for biliary complications after liver transplantation from “donation after cardiac …

Current situation of donation after circulatory death in European countries

B Domínguez‐Gil, B Haase‐Kromwijk… - Transplant …, 2011 - Wiley Online Library
The aim of the present study was to describe the current situation of donation after
circulatory death (DCD) in the Council of Europe, through a dedicated survey. Of 27 …

Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids

F Sampaziotis, AW Justin, OC Tysoe, S Sawiak… - Nature medicine, 2017 - nature.com
The treatment of common bile duct (CBD) disorders, such as biliary atresia or ischemic
strictures, is restricted by the lack of biliary tissue from healthy donors suitable for surgical …

Ischemic cholangiopathy after controlled donation after cardiac death liver transplantation: a meta-analysis

CL Jay, V Lyuksemburg, DP Ladner, E Wang… - Annals of …, 2011 - journals.lww.com
Objective: To conduct a meta-analysis to enhance understanding of the risks of biliary
complications, particularly ischemic cholangiopathy (IC), after donation after cardiac death …