[HTML][HTML] How genomics can help biodiversity conservation

K Theissinger, C Fernandes, G Formenti, I Bista… - Trends in Genetics, 2023 - cell.com
The availability of public genomic resources can greatly assist biodiversity assessment,
conservation, and restoration efforts by providing evidence for scientifically informed …

Genetic load: genomic estimates and applications in non-model animals

G Bertorelle, F Raffini, M Bosse, C Bortoluzzi… - Nature Reviews …, 2022 - nature.com
Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …

Genetic diversity loss in the Anthropocene

M Exposito-Alonso, TR Booker, L Czech, L Gillespie… - Science, 2022 - science.org
Anthropogenic habitat loss and climate change are reducing species' geographic ranges,
increasing extinction risk and losses of species' genetic diversity. Although preserving …

Population genomics of the critically endangered kākāpō

N Dussex, T Van Der Valk, HE Morales, CW Wheat… - Cell Genomics, 2021 - cell.com
The kākāpō is a flightless parrot endemic to New Zealand. Once common in the archipelago,
only 201 individuals remain today, most of them descending from an isolated island …

Deleterious variation in natural populations and implications for conservation genetics

J Robinson, CC Kyriazis, SC Yuan… - Annual review of …, 2023 - annualreviews.org
Deleterious mutations decrease reproductive fitness and are ubiquitous in genomes. Given
that many organisms face ongoing threats of extinction, there is interest in elucidating the …

Ancient and modern genomes unravel the evolutionary history of the rhinoceros family

S Liu, MV Westbury, N Dussex, KJ Mitchell… - Cell, 2021 - cell.com
Only five species of the once-diverse Rhinocerotidae remain, making the reconstruction of
their evolutionary history a challenge to biologists since Darwin. We sequenced genomes …

New developments in the field of genomic technologies and their relevance to conservation management

G Segelbacher, M Bosse, P Burger, P Galbusera… - Conservation …, 2022 - Springer
Recent technological advances in the field of genomics offer conservation managers and
practitioners new tools to explore for conservation applications. Many of these tools are well …

Ancient and historical DNA in conservation policy

EL Jensen, D Díez-del-Molino, MTP Gilbert… - Trends in Ecology & …, 2022 - cell.com
Although genetic diversity has been recognized as a key component of biodiversity since the
first Convention on Biological Diversity (CBD) in 1993, it has rarely been included in …

From high masked to high realized genetic load in inbred Scandinavian wolves

L Smeds, H Ellegren - Molecular Ecology, 2023 - Wiley Online Library
When new mutations arise at functional sites they are more likely to impair than improve
fitness. If not removed by purifying selection, such deleterious mutations will generate a …

Conservation management strategy impacts inbreeding and mutation load in scimitar-horned oryx

E Humble, MA Stoffel, K Dicks… - Proceedings of the …, 2023 - National Acad Sciences
In an age of habitat loss and overexploitation, small populations, both captive and wild, are
increasingly facing the effects of isolation and inbreeding. Genetic management has …