The imbalance of intestinal microecology firstly impairs intestinal mucosa barrier and
function, then further damages the functions and homeostasis of distal organs, leading to …

DNA methylation is a vital modification process in the control of genetic information, which
contributes to the epigenetics by regulating gene expression without changing the DNA …

It is well known that phenotype of animals may be modified by the nutritional modulations
through epigenetic mechanisms. As a key and central component of epigenetic network …

Diet bioactive components, in the concept of nutrigenetics and nutrigenomics, consist of food
constituents, which can transfer information from the external environment and influence …

Abstract Background In 1957, Francis Crick drew a linear diagram on a blackboard. This
diagram is often called the “central dogma.” Subsequently, the relationships between …

Dietary folate is a major source of methyl groups required for DNA methylation, an
epigenetic modification that is actively maintained and remodeled during spermatogenesis …

Microorganisms that colonize the gastrointestinal tract, collectively known as the gut
microbiota, are known to produce small molecules and metabolites that significantly …

Genome-wide epigenetic changes in plants are being reported during development and
environmental stresses, which are often correlated with gene expression at the …

During range expansions, organisms are often exposed to multiple pressures, including
novel enemies (ie, predators, competitors and/or parasites) and unfamiliar or limited …

Doxorubicin (DOX), a potent and broad-spectrum antineoplastic agent, causes an
irreversible, cumulative and dose-dependent cardiomyopathy that ultimately leads to …