Applications and advances of multicellular tumor spheroids: challenges in their development and analysis

AG Mitrakas, A Tsolou, S Didaskalou… - International Journal of …, 2023 - mdpi.com
Biomedical research requires both in vitro and in vivo studies in order to explore disease
processes or drug interactions. Foundational investigations have been performed at the …

DNA dyes—highly sensitive reporters of cell quantification: comparison with other cell quantification methods

A Ligasová, K Koberna - Molecules, 2021 - mdpi.com
Cell quantification is widely used both in basic and applied research. A typical example of its
use is drug discovery research. Presently, plenty of methods for cell quantification are …

[HTML][HTML] Seaweed polysaccharides as macromolecular crowding agents

A De Pieri, S Rana, S Korntner, DI Zeugolis - International Journal of …, 2020 - Elsevier
Abstract Development of mesenchymal stem cell-based tissue engineered implantable
devices requires prolonged in vitro culture for the development of a three-dimensional …

Lactate dehydrogenase 5 isoenzyme overexpression defines resistance of prostate cancer to radiotherapy

MI Koukourakis, A Giatromanolaki… - British journal of …, 2014 - nature.com
Background: Radiotherapy provides high-cure rates in prostate cancer. Despite its overall
slow clinical growth, high proliferation rates documented in a subset of tumours relate to …

Fever-range hyperthermia vs. hypothermia effect on cancer cell viability, proliferation and HSP90 expression

D Kalamida, IV Karagounis, A Mitrakas, S Kalamida… - PLoS …, 2015 - journals.plos.org
Purpose The current study examines the effect of fever-range hyperthermia and mild
hypothermia on human cancer cells focusing on cell viability, proliferation and HSP90 …

Hypoxia-inducible proteins HIF1α and lactate dehydrogenase LDH5, key markers of anaerobic metabolism, relate with stem cell markers and poor post-radiotherapy …

MI Koukourakis, C Kakouratos, D Kalamida… - … journal of radiation …, 2016 - Taylor & Francis
Purpose: To assess whether anaerobic metabolism, proliferation activity and stem cell
content are linked with radioresistance in bladder cancer. Materials and methods: Tissue …

Silk fibroin nanoscaffolds for neural tissue engineering

R Boni, A Ali, SG Giteru, A Shavandi… - Journal of Materials …, 2020 - Springer
The nervous system is a crucial component of the body and damages to this system, either
by injury or disease, can result in serious or potentially lethal consequences. An important …

Vitrification of particulated articular cartilage via calculated protocols

K Wu, N Shardt, L Laouar, JAW Elliott… - NPJ Regenerative …, 2021 - nature.com
Preserving viable articular cartilage is a promising approach to address the shortage of graft
tissue and enable the clinical repair of articular cartilage defects in articulating joints, such …

HOXB9 Overexpression Promotes Colorectal Cancer Progression and Is Associated with Worse Survival in Liver Resection Patients for Colorectal Liver Metastases

E Martinou, C Moller-Levet, D Karamanis… - International journal of …, 2022 - mdpi.com
As is known, HOXB9 is an important factor affecting disease progression and overall survival
(OS) in cancer. However, its role in colorectal cancer (CRC) remains unclear. We aimed to …

Bioinspired cell-in-shell systems in biomedical engineering and beyond: Comparative overview and prospects

LSH Chong, J Zhang, KS Bhat, D Yong, J Song - Biomaterials, 2021 - Elsevier
With the development in tissue engineering, cell transplantation, and genetic technologies,
living cells have become an important therapeutic tool in clinical medical care. For various …