Astrocytes in human central nervous system diseases: a frontier for new therapies
A Verkhratsky, A Butt, B Li, P Illes, R Zorec… - … and Targeted Therapy, 2023 - nature.com
Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis
and defence of the central nervous system (CNS). Astroglia contribute to the …
and defence of the central nervous system (CNS). Astroglia contribute to the …
Astrocyte energy and neurotransmitter metabolism in Alzheimer's disease: integration of the glutamate/GABA-glutamine cycle
JV Andersen, A Schousboe, A Verkhratsky - Progress in neurobiology, 2022 - Elsevier
Astrocytes contribute to the complex cellular pathology of Alzheimer's disease (AD).
Neurons and astrocytes function in close collaboration through neurotransmitter recycling …
Neurons and astrocytes function in close collaboration through neurotransmitter recycling …
The spatial transcriptomic landscape of non-small cell lung cancer brain metastasis
Brain metastases (BrMs) are a common occurrence in lung cancer with a dismal outcome.
To understand the mechanism of metastasis to inform prognosis and treatment, here we …
To understand the mechanism of metastasis to inform prognosis and treatment, here we …
Pericytes in the disease spotlight
H van Splunder, P Villacampa, A Martínez-Romero… - Trends in Cell …, 2024 - cell.com
Pericytes are known as the mural cells in small-caliber vessels that interact closely with the
endothelium. Pericytes play a key role in vasculature formation and homeostasis, and when …
endothelium. Pericytes play a key role in vasculature formation and homeostasis, and when …
Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies
I Lurje, NT Gaisa, R Weiskirchen, F Tacke - Molecular Aspects of Medicine, 2023 - Elsevier
Fibrosis, or tissue scarring, develops as a pathological deviation from the physiological
wound healing response and can occur in various organs such as the heart, lung, liver …
wound healing response and can occur in various organs such as the heart, lung, liver …
Molecular anatomy of adult mouse leptomeninges
R Pietilä, F Del Gaudio, L He, E Vázquez-Liébanas… - Neuron, 2023 - cell.com
Leptomeninges, consisting of the pia mater and arachnoid, form a connective tissue
investment and barrier enclosure of the brain. The exact nature of leptomeningeal cells has …
investment and barrier enclosure of the brain. The exact nature of leptomeningeal cells has …
Fibroblast and myofibroblast activation in normal tissue repair and fibrosis
The term 'fibroblast'often serves as a catch-all for a diverse array of mesenchymal cells,
including perivascular cells, stromal progenitor cells and bona fide fibroblasts. Although …
including perivascular cells, stromal progenitor cells and bona fide fibroblasts. Although …
Living on the edge of the CNS: meninges cell diversity in health and disease
The meninges are the fibrous covering of the central nervous system (CNS) which contain
vastly heterogeneous cell types within its three layers (dura, arachnoid, and pia). The dural …
vastly heterogeneous cell types within its three layers (dura, arachnoid, and pia). The dural …
[HTML][HTML] Pericytes in the tumor microenvironment
Z Jiang, J Zhou, L Li, S Liao, J He, S Zhou, Y Zhou - Cancer letters, 2023 - Elsevier
Pericytes are a type of mural cell located between the endothelial cells of capillaries and the
basement membrane, which function to regulate the capillary vasomotor and maintain …
basement membrane, which function to regulate the capillary vasomotor and maintain …
Pathophysiology, classification and comorbidities after traumatic spinal cord injury
J Guest, N Datta, G Jimsheleishvili… - Journal of personalized …, 2022 - mdpi.com
The spinal cord is a conduit within the central nervous system (CNS) that provides ongoing
communication between the brain and the rest of the body, conveying complex sensory and …
communication between the brain and the rest of the body, conveying complex sensory and …