Effect of saffron, black seed, and their main constituents on inflammatory cytokine response (mainly TNF-α) and oxidative stress status: An aspect on pharmacological …
Z Vafaeipour, M Ghasemzadeh Rahbardar… - Naunyn-Schmiedeberg's …, 2023 - Springer
Tumor necrosis factor-α (TNF-α), an inflammatory cytokine, is produced by monocytes and
macrophages. It is known as a'double-edged sword'because it is responsible for …
macrophages. It is known as a'double-edged sword'because it is responsible for …
Adrenomedullin mitigates doxorubicin-induced nephrotoxicity in rats: role of oxidative stress, inflammation, apoptosis, and pyroptosis
Doxorubicin (DOX) is an anticancer antibiotic which has various effects in human cancers. It
is one of the commonly known causes of drug-induced nephrotoxicity, which results in acute …
is one of the commonly known causes of drug-induced nephrotoxicity, which results in acute …
Betaine alleviates doxorubicin‐induced nephrotoxicity by preventing oxidative insults, inflammation, and fibrosis through the modulation of Nrf2/HO− 1/NLRP3 and …
Doxorubicin (Dox) is an anthracycline antibiotic used to treat various cancers and shows
severe toxicity in multiple organ systems, including kidneys. Evidence shows that betaine's …
severe toxicity in multiple organ systems, including kidneys. Evidence shows that betaine's …
Emerging insights into the role of NLRP3 inflammasome and endoplasmic reticulum stress in renal diseases
Y Zhang, S Guo, X Fu, Q Zhang, H Wang - International …, 2024 - Elsevier
NLRP3 inflammasome is a key component of the innate immune system, mediating the
activation of caspase-1, and the maturity and secretion of the pro-inflammatory cytokine …
activation of caspase-1, and the maturity and secretion of the pro-inflammatory cytokine …
[HTML][HTML] Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin
Objective (s): Due to its negative side effects, mainly nephrotoxicity, adriamycin (ADR) is
used fairly infrequently. The purpose of this study is to investigate the effects of N-acetyl …
used fairly infrequently. The purpose of this study is to investigate the effects of N-acetyl …
Protective Role of Melatonin Against Abamectin-Induced Biochemical, Immunohistochemical, and Ultrastructural Alterations in the Testicular Tissues of Rats
C Adiguzel, H Karaboduk… - Microscopy and …, 2024 - academic.oup.com
Abamectin is one of the most widely used pesticides due to its strong insecticidal and
anthelmintic activities. Melatonin is a neurohormone with potent antioxidant, anti-apoptotic …
anthelmintic activities. Melatonin is a neurohormone with potent antioxidant, anti-apoptotic …
Ameliorative effects of thymoquinone on the caspase 3, kidney function and oxidative stress tartrazine-induced nephrotoxicity
Z Erdemli, M Gul, N Gokturk, E Kayhan, N Demircigil… - Toxicon, 2024 - Elsevier
First in the literature this study aimed to investigate the effects of Tartrazine, a common
industrial food dye, on kidney and whether Thymoquinone has a protective effect in …
industrial food dye, on kidney and whether Thymoquinone has a protective effect in …
Crocin, the compound of the dried stigma of Crocus sativus L (saffron), restores doxorubicin-induced disturbances in kidney functioning, oxidative stress, inflammation …
E Altinoz, D Cetinavci… - Natural Product …, 2024 - Taylor & Francis
Doxorubicin (Dox), an anthracycline antibiotic, is a chemotherapeutic drug for several
cancer treatments. However, its clinical usage has been restricted because of severe side …
cancer treatments. However, its clinical usage has been restricted because of severe side …
Thymoquinone: An Effective Natural Compound for Kidney Protection
H Zhang, Y Liu, Y Dong, G Li, S Wang - The American Journal of …, 2024 - World Scientific
Kidney disease is a common health problem worldwide. Acute or chronic injuries may
interfere with kidney functions, eventually resulting in irreversible kidney damage. A number …
interfere with kidney functions, eventually resulting in irreversible kidney damage. A number …
Evaluation of the protective effect of losartan in acetaminophen-induced liver and kidney damage in mice
Acetaminophen is widely used among humans as an antipyretic and analgesic. In this study,
the protective effect of losartan in hepatotoxicity and nephrotoxicity induced by …
the protective effect of losartan in hepatotoxicity and nephrotoxicity induced by …