Our current knowledge of human memory CD8+ T cells is derived largely from studies of the
intravascular space. However, emerging data are starting to challenge some of the dogmas …

Immunological memory is a hallmark of adaptive immunity and facilitates an accelerated and
enhanced immune response upon re-infection with the same pathogen,. Since the outbreak …

Chronic antigen exposure during viral infection or cancer promotes an exhausted T cell
(Tex) state with reduced effector function. However, whether all antigen-specific T cell clones …

T cells differentiate into functionally distinct states upon antigen encounter. These states are
delineated by different cell surface markers for murine and human T cells, which hamper …

Invariant natural killer T (iNKT) cells are a unique T lymphocyte population expressing semi-
invariant T cell receptors (TCRs) that recognise lipid antigens presented by CD1d. iNKT …

Cell types can be classified according to shared patterns of transcription. Non-genetic
variability among individual cells of the same type has been ascribed to stochastic …

The in vivo phenotypic profile of T cells reactive to severe acute respiratory syndrome
(SARS)-CoV-2 antigens remains poorly understood. Conventional methods to detect …

CD8 T cells have multiple functional properties that mediate acute phase and long-term
immune protection. Several effector and memory CD8 T cell subsets have been described …

The surface of HIV-1 is embedded with numerous host-derived proteins. Characterizing
these proteins can enhance knowledge of virus biology and potentially identify novel …

The uterine immune system is crucial for the establishment of a healthy pregnancy and
further development of the embryo. Although a lot is known about endometrial immune cell …