Intrahepatic hypothyroidism in MASLD: Role of liver-specific thyromimetics including resmetirom
MS Kuchay, S Isaacs, A Misra - … & Metabolic Syndrome: Clinical Research & …, 2024 - Elsevier
Background and aims Thyroid hormones are important regulators of hepatic lipid
homeostasis and whole-body energy expenditure. Recent evidence suggests that euthyroid …
homeostasis and whole-body energy expenditure. Recent evidence suggests that euthyroid …
Actions of thyroid hormones and thyromimetics on the liver
Thyroid hormones (triiodothyronine and thyroxine) are pivotal for metabolic balance in the
liver and entire body. Dysregulation of the hypothalamus–pituitary–thyroid axis can …
liver and entire body. Dysregulation of the hypothalamus–pituitary–thyroid axis can …
[PDF][PDF] Clinical Research & Reviews
MS Kuchay, S Isaacs, A Misra - Diabetes & Metabolic Syndrome …, 2024 - researchgate.net
Background and aims: Thyroid hormones are important regulators of hepatic lipid
homeostasis and whole-body energy expenditure. Recent evidence suggests that euthyroid …
homeostasis and whole-body energy expenditure. Recent evidence suggests that euthyroid …
Synthetic Thyroid Hormone Receptor-β Agonists Promote Oligodendrocyte Precursor Cell Differentiation in the Presence of Inflammatory Challenges
VA Baldassarro, C Quadalti, M Runfola, C Manera… - Pharmaceuticals, 2023 - mdpi.com
Oligodendrocytes and their precursors are the cells responsible for developmental
myelination and myelin repair during adulthood. Their differentiation and maturation …
myelination and myelin repair during adulthood. Their differentiation and maturation …
[HTML][HTML] 3D culture models to study pathophysiology of steatotic liver disease
Steatotic liver disease (SLD) refers to a spectrum of diseases caused by hepatic lipid
accumulation. SLD has emerged as the leading cause of chronic liver disease worldwide …
accumulation. SLD has emerged as the leading cause of chronic liver disease worldwide …
[HTML][HTML] Drug discovery targeting thyroid hormone receptor β (THRβ) for the treatment of liver diseases and other medical indications
K Wang, F Chen, J Wang, H Liu - Acta Pharmaceutica Sinica B, 2024 - Elsevier
Thyroid hormone receptors (THRs), a crucial nuclear receptor protein family, primarily
consist of two categories: α receptors and β receptors. Among them, THRβ is the primary …
consist of two categories: α receptors and β receptors. Among them, THRβ is the primary …
代谢相关脂肪性肝病靶向药物治疗进展
宗廷妮, 戴光荣, 赵晓宇, 李瑞风, 柴聪敏 - 临床荟萃, 2023 - huicui.hebmu.edu.cn
代谢相关脂肪性肝病的患病率逐年上升, 已成为我国最常见的慢性肝脏疾病,
严重危害人类健康并对社会造成了巨大的经济负担. 目前代谢相关脂肪性肝病的一线治疗主要是 …
严重危害人类健康并对社会造成了巨大的经济负担. 目前代谢相关脂肪性肝病的一线治疗主要是 …