Nigella sativa L. Phytochemistry and Pharmacological Activities: A Review (2019–2021)

M Dalli, O Bekkouch, S Azizi, A Azghar, N Gseyra… - Biomolecules, 2021 - mdpi.com
Medicinal and aromatic plants are mainly characterized by the presence of different
bioactive compounds which exhibit various therapeutic activities. In order to investigate the …

Pharmacologic effects approach of essential oils and their components on respiratory diseases

J Li, W Chen, H Liu, H Liu, S Xiang, F You… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Essential oils (EOs) are concentrated
hydrophobic liquids with volatility and a unique aroma. Formed by aromatic plants as …

Bioactivity of chitosan-based particles loaded with plant-derived extracts for biomedical applications: Emphasis on antimicrobial fiber-based systems

JC Antunes, JM Domingues, CS Miranda, AFG Silva… - Marine Drugs, 2021 - mdpi.com
Marine-derived chitosan (CS) is a cationic polysaccharide widely studied for its bioactivity,
which is mostly attached to its primary amine groups. CS is able to neutralize reactive …

[HTML][HTML] In vitro and in silico approaches for the evaluation of antimicrobial activity, time-kill kinetics, and anti-biofilm potential of thymoquinone (2-Methyl-5-propan-2 …

KA Qureshi, M Imtiaz, A Parvez, PK Rai, M Jaremko… - Antibiotics, 2022 - mdpi.com
Thymoquinone (2-methyl-5-propan-2-ylcyclohexa-2, 5-diene-1, 4-dione; TQ), a principal
bioactive phytoconstituent of Nigella sativa essential oil, has been reported to have high …

Exploring the potential of natural product-based nanomedicine for maintaining oral health

R Kumar, MA Mirza, PP Naseef, MS Kuruniyan, F Zakir… - Molecules, 2022 - mdpi.com
Oral diseases pose a major threat to public health across the globe. Diseases such as
dental caries, periodontitis, gingivitis, halitosis, and oral cancer affect people of all age …

Safety and Therapeutic Efficacy of Thymoquinone-Loaded Liposomes against Drug-Sensitive and Drug-Resistant Acinetobacter baumannii

KS Allemailem, AM Alnuqaydan, A Almatroudi… - Pharmaceutics, 2021 - mdpi.com
In the present study, we investigated the activity of free thymoquinone (TQ) or liposomal
thymoquinone (Lip-TQ) in comparison to standard antibiotic amoxicillin (AMX) against the …

Efficacy Confirmation Test of Black Cumin (Nigella sativa L.) Seeds Extract Using a High-Fat Diet Mouse Model

KMI Bashir, JW Kim, JK Kim, YS Chun, JS Choi, SK Ku - Metabolites, 2023 - mdpi.com
To deal with the adverse effects associated with the use of currently available treatments for
metabolic disorders, such as type 2 diabetes, there is a need to find an alternative drug …

Antimicrobial, Immunomodulatory and Anti-Inflammatory Potential of Liposomal Thymoquinone: Implications in the Treatment of Bacterial Pneumonia in …

KS Allemailem, A Almatroudi, F Alrumaihi… - Biomedicines, 2021 - mdpi.com
Acinetobacter baumannii has recently been increasing as an aggressive pathogen in
immunocompromised persons. In the present study, we determined the in vitro antibacterial …

Molecular insight into thymoquinone mechanism of action against Mycobacterium tuberculosis

G Jankowski, R Sawicki, W Truszkiewicz… - Frontiers in …, 2024 - frontiersin.org
Natural products are promising antimicrobials, usually having multiple and different cellular
targets than synthetic antibiotics. Their influence on bacteria at various metabolic and …

Lippia graveolens Essential Oil to Enhance the Effect of Imipenem against Axenic and Co-Cultures of Pseudomonas aeruginosa and Acinetobacter baumannii

JO Fimbres-García, M Flores-Sauceda, ED Othón-Díaz… - Antibiotics, 2024 - mdpi.com
This research focuses on assessing the synergistic effects of Mexican oregano (Lippia
graveolens) essential oil or carvacrol when combined with the antibiotic imipenem, aiming to …