Next-generation influenza vaccines: opportunities and challenges
CJ Wei, MC Crank, J Shiver, BS Graham… - Nature reviews Drug …, 2020 - nature.com
Seasonal influenza vaccines lack efficacy against drifted or pandemic influenza strains.
Developing improved vaccines that elicit broader immunity remains a public health priority …
Developing improved vaccines that elicit broader immunity remains a public health priority …
Dendritic cells in COVID-19 immunopathogenesis: insights for a possible role in determining disease outcome
RC Borges, MS Hohmann… - International Reviews of …, 2021 - Taylor & Francis
SARS-CoV-2 is the causative agent of the COVID-19 pandemic. This novel coronavirus
emerged in China, quickly spreading to more than 200 countries worldwide. Although most …
emerged in China, quickly spreading to more than 200 countries worldwide. Although most …
Humoral and circulating follicular helper T cell responses in recovered patients with COVID-19
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
dramatically expedited global vaccine development efforts,–, most targeting the viral …
dramatically expedited global vaccine development efforts,–, most targeting the viral …
Integrated immune dynamics define correlates of COVID-19 severity and antibody responses
SARS-CoV-2 causes a spectrum of COVID-19 disease, the immunological basis of which
remains ill defined. We analyzed 85 SARS-CoV-2-infected individuals at acute and/or …
remains ill defined. We analyzed 85 SARS-CoV-2-infected individuals at acute and/or …
Reduced blood-stage malaria growth and immune correlates in humans following RH5 vaccination
Background Development of an effective vaccine against the pathogenic blood-stage
infection of human malaria has proved challenging, and no candidate vaccine has affected …
infection of human malaria has proved challenging, and no candidate vaccine has affected …
Maintenance of broad neutralizing antibodies and memory B cells 1 year post-infection is predicted by SARS-CoV-2-specific CD4+ T cell responses
Understanding the long-term maintenance of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) immunity is critical for predicting protection against reinfection …
coronavirus 2 (SARS-CoV-2) immunity is critical for predicting protection against reinfection …
Immune dynamics in SARS-CoV-2 experienced immunosuppressed rheumatoid arthritis or multiple sclerosis patients vaccinated with mRNA-1273
NJM Verstegen, RR Hagen, J van den Dijssel… - Elife, 2022 - elifesciences.org
Background: Patients affected by different types of autoimmune diseases, including common
conditions such as multiple sclerosis (MS) and rheumatoid arthritis (RA), are often treated …
conditions such as multiple sclerosis (MS) and rheumatoid arthritis (RA), are often treated …
[HTML][HTML] Sensitization in transplantation: assessment of risk (STAR) 2019 working group meeting report
The purpose of the STAR 2019 Working Group was to build on findings from the initial STAR
report to further clarify the expectations, limitations, perceptions, and utility of alloimmune …
report to further clarify the expectations, limitations, perceptions, and utility of alloimmune …
The immune response to SARS-CoV-2 and variants of concern
At the end of 2019 a newly emerged betacoronavirus, severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), was identified as the cause of an outbreak of severe …
coronavirus 2 (SARS-CoV-2), was identified as the cause of an outbreak of severe …
Protein/AS01B vaccination elicits stronger, more Th2-skewed antigen-specific human T follicular helper cell responses than heterologous viral vectors
Interactions between B cells and CD4+ T follicular helper (Tfh) cells are key determinants of
humoral responses. Using samples from clinical trials performed with the malaria vaccine …
humoral responses. Using samples from clinical trials performed with the malaria vaccine …